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false/phosphatase
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Avoiding false discovery in biomarker research.
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Human tyrosine-protein phosphatase non-receptor type substrate 1α (SIRPA) is a surface marker identified in cardiomyocytes differentiated from human embryonic stem cells. Our objective was to determine if circulating SIRPA levels can serve as a biomarker of cardiac injury in children undergoing open
Can acid phosphatase reduce pap test false-negative readings?
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Elevated bone marrow acid phosphatase: the problem of false positives.
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Bone marrow acid phosphatase values were studied in 24 patients (12 men and 12 women) selected at random, including 6 at autopsy. False positive results were noted in 8 of the 18 patients who were alive and in all 6 patients studied at autopsy. The possible causes for these falsely elevated results
False Positive Phosphatase Test from a Thermophil in Pasteurized Milk.
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Re: elevated bone marrow acid phosphatase: the problem of false positives.
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Evaluation of specific antigen and prostatic acid phosphatase specificity. Study of false values.
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We assayed prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) serum levels in 1305 subjects without malignant prostatic pathology by double antibody RIA I125 to evaluate their specificity. When we set a second upper normal limit of 10 ng/ml for PSA and 2.5 ng/ml for PAP there was
Fusion proteins could generate false positives in peptide phage display.
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Fusion proteins are frequently used in the functional characterization of newly discovered proteins and to identify interacting partners. In our study of hPTP1E, a cytosolic protein tyrosine phosphatase, we used glutathione S-transferase (GST)-fusion protein of the second PDZ domain to identify
High acid phosphatase levels as a possible false indicator of the presence of seminal fluid.
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False Positive Troponin I Rendering Two Admissions for "Recurrent Acute Myopericarditis".
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UNASSIGNED
Since there are many manufacturers of cardiac troponin I assays, the true incidence of a false positive result is unknown. The authors report a case of an 18-year-old patient with previous history of recurrent myopericarditis and admitted to hospital twice again with a suspicious of
False localization of acid phosphatase activity in the nuclear envelope and endoplasmic reticulum of peritoneal macrophages.
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Acid phosphatase cytochemistry using lead salt methods was performed on rat peritoneal macrophages obtained by the intraperitoneal injection of dextran five days previously. Lead precipitate was present in the nuclear envelope, the rough endoplasmic reticulum, Golgi apparatus and lysosomes in about
[False positive serum des-gamma-carboxy prothrombin after resection of hepatocellular carcinoma].
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Measurements of serum concentrations of des-gamma-carboxy-prothrombin (PIVKA-II) are widely used for diagnosing hepatocellular carcinoma (HCC). Recently, when we evaluated the correlation of PIVKA-II between two commercially available PIVKA-II immunoassay kits (Lumipulse f vs. Picolumi) to introduce
False-negative biopsy for testicular intraepithelial neoplasia and high-risk features for testicular cancer.
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The purpose of this report is to emphasize the possibility of false-negative biopsies for testicular intraepithelial neoplasia (TIN) in men with high-risk features of testicular cancer and to review the relevant literature. At the Norwegian Radium Hospital patients in this category are offered the
A transformer of molecular beacon for sensitive and real-time detection of phosphatases with effective inhibition of the false positive signals.
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Molecular beacons (MBs) have shown great potential in measurement of enzyme activities. However, currently available methods for monitoring of phosphatases only use MBs as a signal reporter. Extra substrates for the phosphatases are needed to hybridize to the MB either as a primer or as a template.
False positive values of PAP and PSA in complicated and non-complicated benign prostatic hypertrophy.
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Cancer of the prostate has become the most frequent form of cancer in men. Different tests have been used in cancer of the prostate, including prostate acid phosphatase (PAP) and the prostate specific antigen (PSA). Their value as diagnostic screening is disputed, as it is known that there are false
Triggering a false alarm: wounding mimics prey capture in the carnivorous Venus flytrap (Dionaea muscipula).
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In the carnivorous plant Venus flytrap (Dionaea muscipula), the sequence of events after prey capture resembles the well-known plant defence signalling pathway in response to pathogen or herbivore attack. Here, we used wounding to mimic prey capture to show the similarities and differences between
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