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Determinants of COVID-19 Pneumonia (MC-19)

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As demonstrated by a study conducted by Ai et al., including 1014 suspect COVID-19 cases who underwent multiple RT-PCR testing and chest-CT, overall 88% of patients had positive CT scans while RT-PCR positivity was found only in 59% of all cases. Also, as reported by Yang et al, the total positive

Prevalence of Exocrine Pancreatic Insufficiency in Patients With Decompensated Cirrhosis

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Exocrine pancreatic insufficiency (EPI) is defined as the inability of the pancreas to perform a normal digestive function. Habitually, it occurs as a result of a severe reduction in the secretion of pancreatic enzymes, although - less frequently - it may be due to the inability of these enzymes to

LIVER FIBROSIS PREVALENCE IN FRANCE

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"This is the initial version of the FIBROFRANCE project which strated in 1997. Methods The strategy chosen is to screen advanced fibrosis in several groups of patients with different levels of risks in order to reconstruct the French prevalence thereafter. A national screening will be suggested

Alternative Therapies for Menopause: A Randomized Trial

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Over 17 million U.S. women are in the peri- and post-menopausal age range (45 - 55), and by the year 2015 nearly half of U.S. women will be post-menopausal. Of these, 25-33% will experience moderate to severe menopausal symptoms, and all will be faced with decisions related to maintaining their

BH4 Responsiveness in PAH Deficiency PKU Patients

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Objectives 1. Changes of blood Phe level from baseline at the 7th, 14th, and 28th day 2. Percentage of the study patients whose blood Phe level decreases for >= 30% 3. Percentage of the study patients whose Phe tolerance increase from baseline for >=50% 4. Correlation between PAH gene mutation and

Genetic Risk and Health Coaching for Type 2 Diabetes and Coronary Heart Disease

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This study will examine the impact of providing genetic CHD and T2D risk information, with or without a supportive behavioral intervention, on promoting risk-reducing behaviors and improving clinical outcomes. In short, using a 4-group (2X2) randomized controlled trial (RCT) design, this study will

Community-based Screening of Chronic Kidney Disease (CKD) and Measure the Impact of Health Education

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This would be a community-based randomized controlled trial (RCT) among the individuals diagnosed as having CKD with stage 1-3 who agreed to participate. Registration/Enrolment of participants: Community health workers (CHWs) will perform home -visits to obtain written informed consent, perform

Dietary Effects on Lipoproteins and Thrombogenic Activity (DELTA)

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BACKGROUND: A solid foundation of epidemiologic, clinical and laboratory evidence underlies the current dietary recommendations for population-based prevention of coronary heart disease. Average blood cholesterol levels will decline with the consumption of less saturated fat and cholesterol than has

Effect of Including Fitness Testing in Preventive Health Checks on Cardiorespiratory Fitness and Motivation

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BACKGROUND Changing unhealthy lifestyle improves health and reduces morbidity. Motivation is a key component in initiation and maintenance of lifestyle changes. Identifying and motivating individuals with unhealthy lifestyle to change behaviour may be achieved through preventive health checks as

Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)

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Research design This study is a double blind randomized clinical trial to determine differences in wave amplitude P50 and N95 on pattern ERG examination, visual field defects (LP) with Humphrey HFA (Humphrey Field Analyzer) II-i 750, 24-2 threshold and ganglion cell thickness with OCT CirrusTM

Ziprasidone for Clozapine- or Olanzapine-Associated Diabetes Mellitus

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Specific Aims: This study is a six-week, open label trial of the novel antipsychotic agent, ziprasidone, added to a stable dose of clozapine or olanzapine in 40 diabetes mellitus patients, patients with an impaired fasting glucose or insulin resistance with schizophrenia or schizoaffective

Health in Childhood Following Assisted Reproductive Technology

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The investigators aim to conduct a clinical follow-up study of three groups of children: Exposed children conceived by ART(assisted reproductive technology) after frozen embryo transfer (FET) and two unexposed control groups; (1) Children conceived by ART after fresh embryo transfer and (2)

The Effect of Curcumin on the Development of Prednisolone-induced Hepatic Insulin Resistance

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AIMS OF STUDY The aim of this study is to investigate whether ingestion of curcumin will prevent hepatic insulin resistance (assessed by homeostatic model assessment of insulin resistance (HOMA-IR)) induced by short-term oral glucocorticoid (prednisolone) administration in overweight and obese

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