4 resultados
OBJECTIVE
High speed counter current chromatography was successfully applied to the preparative separation of the component of Gentiana scabra Bunge.
METHODS
Gentiopicrin was obtained by preparative HSCCC with two phase solvent system com-posed of chloroform-methanol-tert-butylmethyl-water
A new strongly bitter acyl secoiridoid glucoside, scabraside, has been isolated along with two known secoiridoid glucosides, trifloroside and gentiopicroside (= gentiopicrin), from the rhizomes and roots of GENTIANA SCABRA var. BUERGERI. The structure of the scabraside was established by chemical
BACKGROUND
Gentiana scabra root extract (GS) is frequently prescribed as an internal remedy in traditional Korean medicine for treatment of diabetes mellitus. GS contains bitter iridoid glycosides including loganic acid, gentiopicrin, trifloroside, and rindoside. We previously reported that the
The roots and rhizomes of Gentiana scabra Bunge in the family Gentianaceae comprise a major herbal medicine for skin diseases caused by wind-heat or dampness-heat in China, Japan and Korea. This treatment can clear away heat and dry dampness and purge fire from the liver and