gentiopicrin/gentiana

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[Preparative separation of gentiopicrin from Gentiana scabra bunge by high speed counter current chromatography].

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OBJECTIVE High speed counter current chromatography was successfully applied to the preparative separation of the component of Gentiana scabra Bunge. METHODS Gentiopicrin was obtained by preparative HSCCC with two phase solvent system com-posed of chloroform-methanol-tert-butylmethyl-water

Gentiopicrin-producing endophytic fungus isolated from Gentiana macrophylla.

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Gentiana macrophylla is a traditional Chinese medicinal plant. Its dominant active constituents are secoiridoids, mainly gentiopicrin. The objective of this study was to determine whether endophytic fungi isolated from this plant produce the bioactive ingredient gentiopicrin. Primary screening was

Chemical and Morphological Inter- and Intrapopulation Variability in Natural Populations of Gentiana pneumonanthe L.

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Inter- and intrapopulation variability in six natural populations of the rare species Gentiana pneumonanthe was examined based on morphological and chemical data. Population size and linear morphometric parameters differed significantly among populations, but without a clear connection to habitat

Gentiana clusii Perr.&Song.: Enhanced production of secondary metabolites by in vitro propagation

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Shoot and root in vitro culture of endemic European species Gentiana clusii was established for the first time. The effects of different concentrations of benzyl adenine (BA), 6-phurphurylaminopurine (KIN), indole-3-butyric acid (IBA) and naphthalene acetic acid (NAA) on shoot propagation and

A New Bitter Secoiridoid Glucoside from Gentiana scabra var. Buergeri.

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A new strongly bitter acyl secoiridoid glucoside, scabraside, has been isolated along with two known secoiridoid glucosides, trifloroside and gentiopicroside (= gentiopicrin), from the rhizomes and roots of GENTIANA SCABRA var. BUERGERI. The structure of the scabraside was established by chemical

Effect of gentiopicroside on experimental acute pancreatitis induced by retrograde injection of sodium taurocholate into the biliopancreatic duct in rats.

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Gentiopicroside (otherwise known as Gentiopicrin), one of the main active ingredients from the traditional Chinese herb medicine Gentiana manshurica Kitag, presents the effect of attenuating acute pancreatitis in rats. The experimental acute pancreatitis was made by retrograde injection of sodium

Hepatoprotective effects of secoiridoid-rich extracts from Gentiana cruciata L. against carbon tetrachloride induced liver damage in rats.

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The objective of this work was to investigate the effects of the methanol extracts of Gentiana cruciata L. aerial parts (GCA) and roots (GCR) against carbon tetrachloride-induced liver injury in rats. Pretreatment with GCA and GCR, containing sweroside, swertiamarin and gentiopicrin in high

[Investigation on explovitage of Gentiana straminea].

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Gentiopicrin contents in different organs, habitats and harvest time of Gentiana straminea cultivated at Gansu were determined by high performance liquid chromatography (HPLC). The results showed that the gentiopicrin contents in the plants growing for three years were slightly higher than those of

A bitter herbal medicine Gentiana scabra root extract stimulates glucagon-like peptide-1 secretion and regulates blood glucose in db/db mouse.

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BACKGROUND Gentiana scabra root extract (GS) is frequently prescribed as an internal remedy in traditional Korean medicine for treatment of diabetes mellitus. GS contains bitter iridoid glycosides including loganic acid, gentiopicrin, trifloroside, and rindoside. We previously reported that the

Gentiana scabra Bunge roots alleviates skin lesions of contact dermatitis in mice.

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The roots and rhizomes of Gentiana scabra Bunge in the family Gentianaceae comprise a major herbal medicine for skin diseases caused by wind-heat or dampness-heat in China, Japan and Korea. This treatment can clear away heat and dry dampness and purge fire from the liver and

[Study on the Discrimination of Gentiana Rigescens with Different Processing Methods by Using FTIR Spectroscopy].

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The Processing of traditional Chinese medicine (TCM) is the key to clinical application of TCM, and processing has functions such as enhancing the efficacy, attenuating the toxicity andmoderating medicine property. In order to the realizing safe, reasonable and effective use of medicine in clinical,

Quantitative determination of secoiridoid and gamma-pyrone compounds in Gentiana lutea cultured in vitro.

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The production of secondary metabolites was studied in shoots, roots, and hairy roots of Gentiana lutea obtained in vitro. In shoots, both secoiridoid and gamma-pyrone compounds were detected in amounts similar to those found in aerial parts of plants collected from nature. The most abundant

Hepatoprotective effects of Gentiana asclepiadea L. extracts against carbon tetrachloride induced liver injury in rats.

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This study is an attempt to evaluate the hepatoprotective activity of Gentiana asclepiadea L. against carbon tetrachloride-induced liver injury in rats. Methanol extracts of aerial parts (GAA) and roots (GAR) of G. asclepiadea at doses of 100, 200, and 400mg/ kg b.w. were orally administered to

Antimicrobial activity of Gentiana lutea L. extracts.

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Methanolic extracts of flowers and leaves of Gentiana lutea L., together with the isolated compounds mangiferin, isogentisin and gentiopicrin, were used to investigate the antimicrobial activity of the plant. A variety of Gram-positive and Gram-negative bacteria as well as the yeast Candida albicans

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