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glycyrrhizic acid/dental caries

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ArtículosEnsayos clínicosPatentes
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Traditional vaginal preparations reside in the vaginal cavity for relatively a short period of time, requiring multiple doses in order to attain the desired therapeutic effect. Therefore, mucoadhesive systems appear to be appropriate to prolong the residence time in the vaginal cavity. In the

Molecularly imprinted polymers as drug delivery systems for the sustained release of glycyrrhizic acid.

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OBJECTIVE The aim was to synthesize molecularly imprinted polymers (MIPs) with high recognition properties towards glycyrrhizic acid and to evaluate the performance of these materials to act as base excipients in glycyrrhizic acid sustained release in gastrointestinal simulating fluids. METHODS MIPs
In this work, a new molecularly imprinted solid phase extraction protocol was developed for the selective extraction and purification of glycyrrhizic acid from liquorice roots in aqueous media. The molecularly imprinted polymers (MIPs) for glycyrrhizic acid were prepared by using

Absorption and biotransformation of four compounds in the Guizhi decoction in the gastrointestinal tracts of rats.

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To study the absorption and biotransformation of liquiritin, cinnamic acid, paeoniflorin, and glycyrrhizic acid in the Guizhi decoction (GZD) in the gastrointestinal tracts of rats.A simple and reliable high-performance liquid chromatography method was

Release of isosorbide dinitrate from polymer film dosage forms and absorption of this drug through the oral mucosa of rats.

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In vitro release tests and in vivo absorption measurements of oral cavity dosage forms of isosorbide dinitrate (ISDN) prepared from mixed polymer film systems were conducted. Hydroxypropylcellulose (HPC) and hydroxypropylmethylcellulose phthalate (HPMCP) were used to make the films, and the tests
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