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Hopea Odorata Extract Can Efficiently Kill Breast Cancer Cells and Cancer Stem-Like Cells in Three-Dimensional Culture More Than in Monolayer Cell Culture
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Introduction: The breast cancer cells with CD44+CD24- phenotype are known to play an important role in tumorigenesis, drug resistance, and cancer recurrence. Breast cancer cells with CD44+CD24- phenotype are cultured in
Niosome-encapsulated Balanocarpol: compound isolation, characterisation, and cytotoxicity evaluation against human breast and ovarian cancer cell lines.
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Natural products have been successfully used for treating various ailments since ancient times and currently there are several natural product based anti-cancer agents used as the main therapy to treat cancer patients or as a complimentary treatment to chemotherapy or radiation. Balanocarpol, which
Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival.
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OBJECTIVE
Sphingosine kinase 1 catalyses formation of the bioactive lipid, sphingosine 1-phosphate, which protects cancer cells from apoptosis. Therefore, sphingosine kinase 1 is a novel target for intervention with anti-cancer agents. We have assessed the effect of the anti-cancer agent,
Benzophenones from Guignardia sp. IFB-E028, an endophyte on Hopea hainanensis.
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The first natural S-containing benzophenone dimer, named guignasulfide (3), was isolated from the culture of Guignardia sp. IFB-E028, an endophytic fungus residing in healthy leaves of Hopea hainanensis. Its structure was determined through correlative analyses of its MS, 1D- and 2D-NMR
Methanol extract of Hopea odorata suppresses inflammatory responses via the direct inhibition of multiple kinases.
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BACKGROUND
Hopea odorata Roxb. (Dipterocarpaceae) is a representative Thai ethnopharmacological herbal plant used in the treatment of various inflammation-related diseases. In spite of its traditional use, systematic studies of its anti-inflammatory action have not been performed.
METHODS
The
Neoplaether, a new cytotoxic and antifungal endophyte metabolite from Neoplaconema napellum IFB-E016.
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A new diphenyl ether, named neoplaether, together with five known compounds monomethylsulochrin, physcion, helvolic acid, ergosterol and ergosterol peroxide, was isolated from the culture of Neoplaconema napellum IFB-E016, an endophytic fungus residing in the healthy leaves of Hopea hainanensis. The
Hopea odorata extract inhibits hepatocellular carcinoma via induction of caspase-dependent apoptosis.
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UNASSIGNED
Cancer is a disease with a global burden and is a major and increasing threat to public health. The demand for new modalities to treat and prevent cancer is high. Given the toxic side effects of standard treatments, such as chemotherapy, there is greater research interest in naturally
Selective Cytotoxicity of Some Plant Extracts Against Hepatocellular Carcinoma Cells but Not Mesenchymal Stem Cells: A Pilot Screening
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Introduction: Medicinal plants have been used for disease treatment throughout history, especially in Asia. Vietnam is a tropical country which possesses forests with a diversity of plants; among the plants, many have been historically used as alternative therapies
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