Dry Eye Syndrome

Topical ocular application 4 times per day

ST266

Topical ocular application 4 timer per day

Refresh Lubricant Eye Drops

Price Vision Group

Study of ST266 Eye Drops in Treating Dry Eye

A Randomized, Masked, Active Placebo-controlled Phase 1 Study of Amnion-derived Cellular Cytokine Solution (ACCS) Eye Drops in the Treatment of Dry Eye

National Eye Institute Scoring System: 0=none, 1=mild, 2=moderate, 3=severe

Lissamine green staining of the conjunctiva

Subject will compete OSDI questionnaire at baseline and at 6 weeks

Tear osmolarity (osmoles/liter) measured at baseline and after 6 weeks of treatment

Noveome Biotherapeutics, formerly Stemnion

U.S. Navy Bureau of Medicine

Obesity

D-allulose (psicose), a C-3 epimer of D-fructose, is defined one of the rare sugars since it is rarely found in nature. Rare sugars are monosaccharides which present in small quantities in commercial mixtures of D-glucose and D-fructose obtained from hydrolysis of sucrose or isomerization of D-glucose (5). D-allulose (psicose) has been demonstrated to be a non-calorie monosaccharide which has approximately 70% sweetness of sucrose. Various physiological activities of D-allulose (psicose) have been revealed. Of those, its glucose suppressive effect has been proven by both animal and clinical studies.

D-allulose

erythritol

Faculty of Medicine, Chiang Mai University

Efficacy of D-allulose on Weight and Fat Loss and Insulin Resistance in Non-diabetic Obese Subjects

The Efficacy of D-allulose (Psicose) on Weight and Fat Loss and Insulin Resistance by a Randomized Double-blind, Parallel-group Study in Non-diabetic Obese Subjects

Supawan Buranapin

Assisstant professor

Chiang Mai University

Kagawa University

Blood for DNA isolation (no sequencing, only SNP array) Stool for microbiome analysis Saliva for microbiome analysis Plasma and serum for metabolomics Urine for creatinine analysis

HIV Infections

Onze Lieve Vrouwe Gasthuis

Radboudumc

Erasmus MC

Elisabeth Twee-Steden ziekenhuis

2000 HIV Human Functional Genomics Partnership Program

Change in liver fibrosis measurement by FibroScan (method by Echosens)

Change in liver steatosis measurement by FibroScan (method by Echosens) and liver ultrasound (method developed by Radboudumc)

Recoring of cadiovascular diseases from patient file:
Stroke/ TIA
Angina pectoris
Myocardial infarction
Claudicatio intermittens
Venous thrombo-embolism
Other …

Genome-wide genotype data including >8 million SNPs per individual

Colonizing microbiome profile will be generated from stool and saliva samples

RNA-sequencing will be performed in PBMCs

Metabolomics analysis by multiplex immunoassays will be performed in plasma or serum

Ex vivo cytokine responses of isolated PBMCs to a range of stimuli (TLR ligands, killed pathogens and viral antigen stimuli)

Extensive phenotyping of circulating immune cells by flow cytometry analysis

Note changes in ECG performed at baseline and two years

Ultrasound measurement of intima-media thickness in the carotid artery as a measure for atherosclerosis and cardiovasculr disease risk.

iris/albúmina

Study of ST266 Eye Drops in Treating Dry Eye

Efficacy of D-allulose on Weight and Fat Loss and Insulin Resistance in Non-diabetic Obese Subjects

2000 HIV Human Functional Genomics Partnership Program

La base de datos de hierbas medicinales más completa respaldada por la ciencia