3 resultados
Glioblastoma multiforme (GBM) is one of the deadliest forms of cancer, with an average survival time of approximately 1year despite aggressive surgery, radiotherapy and chemotherapy. Here, we report a preclinical study by which the two main energy pathways of the tumor cells, oxidative
The understanding of the mechanisms of cell-death execution and the role that they play in different diseases opens new therapeutic strategies. Currently, increasing evidence indicates that autophagy is a frequent cell-death mechanism, so the question arises: Could autophagy stimulation be
The group of research directed by Marta Izquierdo (in which I colaborate close to Dra. García-Escudero and other colleagues) has used in the last three years the linamarase/linamarin system for treatment of brain tumors in the rat. This is a killer/suicide method based upon the plant linamarase