loganic acid/gentiana

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[Content determination of loganic acid and gentiopicroside in Tebitan herbal medicines Gentiana macrophylla and G. straminea by HPLC].

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A quantitative method to determine loganic acid and gentiopicroside in Gentiana macrophylla Pall. and Gentiana straminea Maxim. by RP-HPLC was established in this paper. The two compounds were base-isolated on the coloumn of Zorbax SB-C18 (250 mm x 4.6 mm i.d., 5 microm) which eluted with MeOH and

Iridoid glycosides from the flowers of Gentiana macrophylla Pall. ameliorate collagen-induced arthritis in rats.

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BACKGROUND The flowers of Gentiana macrophylla have been usually applied to cure the joint inflammation and rheumatoid arthritis in Traditional Chinese Medicine. OBJECTIVE This work aimed to investigate the anti-rheumatoid arthritic effect and possible mechanism of iridoid glycosides from G.

Secoiridoid glycosides and an antifungal anthranilate derivative from Gentiana tibetica.

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Repetitive chromatography of the methanol extract of the roots of Gentiana tibetica afforded two new secoiridoid glycosides and a novel antifungal anthranilic acid derivative, together with beta-sitosterol, daucosterol, oleanolic acid, loganic acid, gentiopicroside, sweroside,

A Secoiridoid Glucoside from Gentiana scabra var. buergeri.

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A new bitter acylsecoiridoid glucoside, rindoside, has been isolated along with a known iridoid glucoside, loganic acid, from rhizomes and roots of GENTIANA SCABRA var. BUERGERI. The structure of rindoside was established by chemical and spectral evidence.

[Effect of P and K Fertilization on Four Iridoids in Axial and Lateral Root of Gentiana crassicaulis].

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To study the effect of phosphorus( P) and potassium( K) fertilization on four iridoids in axial and lateral root of Gentiana crassicaulis. Field experiment was conducted based on phosphorus and potassium,and the content of four iridoids was analyzed in the axial and lateral root of Gentiana

Rapid preparative separation of six bioactive compounds from Gentiana crassicaulis Duthie ex Burk. using microwave-assisted extraction coupled with high-speed counter-current chromatography.

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A rapid method combining microwave-assisted extraction (MAE) and high-speed counter-current chromatography (HSCCC) was applied for preparative separation of six bioactive compounds including loganic acid (I), isoorientin-4'-O-glucoside (II), 6'-O-β-d-glucopyranosyl gentiopicroside (III),

Efficient methods for isolating five phytochemicals from Gentiana macrophylla using high-performance countercurrent chromatography.

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Efficient high-performance countercurrent chromatography methods were developed to isolate five typical compounds from the extracts of Gentiana macrophylla. n-Butanol-soluble extract of G. macrophylla contained three hydrophilic iridoids, loganic acid (1), swertiamarin (2) and gentiopicroside (3),

Spatial variation profiling of four phytochemical constituents in Gentiana straminea (Gentianaceae).

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Gentiana straminea is the famous Tibetan folk medicine thought to cure various diseases. Historically, the Qinghai-Tibetan region has been considered as the geo-authentic production area of "Mahua Jiao," where large quantities of the medicine are grown. However, there is still little known about the

4'-P-Coumaroyl Iridoid Glucosides from Gentiana pedicellata.

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From flowers and leaves of GENTIANA PEDICELLATA (Gentianaceae), two new iridoids, 4'- P-coumaroyl loganic acid and 4'- P-coumaroyl loganin, have been isolated along with the known iridoid, loganic acid. This is the first report of iridoid glucosides with the 4'-oxygen of the glucose moiety

[Studies on glycosides from Gentiana veitchiorum].

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OBJECTIVE To study the chemical constituents of Gentiana veitchiorum. METHODS The chemical constituents were isolated by chromatography and identified by spectral data. RESULTS Five glycosides, loganic acid (1), gentiopicroside (2), isoorientin 3'-methyl ether (3), isovitexin (4), isoorientin (5)

Establishment of hairy root lines and analysis of iridoids and secoiridoids in the medicinal plant Gentiana scabra.

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BACKGROUND Gentiana scabra is commonly known as 'Longdan' is an important herb in traditional Chinese medicines, commonly used for the treatment of inflammation, anorexia, indigestion and gastric infections. Iridoids and secoiridoids are main bioactive compounds which attributed to the

Chemical and Genetic Comparative Analysis of Gentiana crassicaulis and Gentiana macrophylla.

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Gentiana crassicaulis Duthie ex Burk. and Gentiana macrophylla Pall. are two main sources of Radix Gentianae Macrophyllae (Qinjiao) available in markets, which has a wide range of anti-inflammatory effects and has been extensively used for fighting rheumatoid arthritis. However, they vary in terms

Isolation of iridoid and secoiridoid glycosides and comparative study on Radix gentianae and related adulterants by HPLC analysis.

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HPLC profile guided study led to the isolation of an acylated secoiridoid glycoside, named gentiotrifloroside (1), together with six known compounds, i.e., loganic acid (2), 6-O-beta-d-glucopyranosylgentiopicroside (3), swertiamarin (4), gentiopicroside (5), sweroside (6) and 2

[Simultaneous determination of five iridoids in gentianae macrophyllae radix and their local variety by HPLC].

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This study aims to establish a new method for quality evaluation of Gentianae Macrophyllae Radix by simultaneous determination of five iridoids (loganic acid, 6'-O-beta-D-glucopyranosylgentiopicroside, swertiamarin, gentiopicroside, sweroside), and to detect five iridoids in the root of eight

Simultaneous determination of four secoiridoid and iridoid glycosides in rat plasma by ultra performance liquid chromatography-tandem mass spectrometry and its application to a comparative pharmacokinetic study.

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A simple, reliable and rapid ultra-performance liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous quantification of four secoiridoid (gentiopicroside, swertiamarin, sweroside) and iridoid glycosides (loganic acid), the bio-active ingredients in rat

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