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Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities.
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Microcos paniculata is a large shrub or small tree that grows in several countries in South and Southeast Asia. In the present study, three new piperidine alkaloids, microgrewiapines A-C (1-3), as well as three known compounds, inclusive of microcosamine A (4),
Insecticidal piperidine alkaloid from Microcos paniculata stem bark.
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The stem bark of Microcos paniculata contained a new alkaloid, N-Methyl-6 beta-(deca-1',3',5'-trienyl)-3 beta-methoxy-2 beta-methylpiperidine, which showed good insecticidal activity against Aedes aegypti second instar larvae.
Two new piperidine alkaloids from the leaves of Microcos paniculata.
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Two new piperidine alkaloids, microcosamines A (1) and B (2), were isolated from the leaves of Microcos paniculata. Their structures were elucidated by spectroscopic analysis. Both new compounds showed significant larvicidal activity against Culex quinquefasciatus.
A new piperidine alkaloid from the leaves of Microcos paniculata L.
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A new piperidine alkaloid, microcosamine C (1), and one known compound, microcosamine A (2) were isolated from the leaves of Microcos paniculata. Structure elucidation was carried out using HR-ESI-MS, 1D and 2D NMR spectroscopic methods and by comparison with data reported in the literature. The
[Seperation and structure elucidation of alkaloids from Chinese drug buzhaye, Folium Microcos].
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From the chloroform extracts of the dried Folium Microcos, four compounds were isolated by using repeated column chromatography on silica gel and recrystallization and their structures were elucidated by physicochemical properties and UV, MS and NMR, separately. They are N-methyl-6alpha-(deca-1',
Qualitative phytochemical screening and evaluation of anti-inflammatory, analgesic and antipyretic activities of Microcos paniculata barks and fruits.
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OBJECTIVE
The main objectives of this study were to qualitatively evaluate the profile of phytochemical constituents present in methanolic extract of Microcos paniculata bark (BME) and fruit (FME), as well as to evaluate their anti-inflammatory, analgesic and antipyretic
Microcos paniculata: a review on its botany, traditional uses, phytochemistry and pharmacology.
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The shrub Microcos paniulata (MPL; Tiliaceae), distributed in south China, south and southeast Asia, yields a phytomedicine used to treat heat stroke, fever, dyspepsia, diarrhea, insect bites and jaundice. Phytochemical investigations on different parts of MPL indicate the presence of flavonoids,
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