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7 resultados
Conjugates of noscapine and folic acid and their use in treating cancer
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FIELD OF THE INVENTION
The present invention relates to novel methods and compositions for treating primary and metastatic cancers and other proliferative disorders. These methods and compositions use conjugates of noscapine or noscapine analogs with folic acid or folic acid analogs. These
Noscapine analogs and their use in treating cancers
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FIELD OF THE INVENTION
The present invention relates to noscapine analogs, pharmaceutical compositions incorporating the noscapine analogs, and methods of using the compounds and compositions to treat cancers, including drug resistant cancers.
BACKGROUND OF THE INVENTION
Microtubules are major
9-aminonoscapine and its use in treating cancers, including drug-resistant cancers
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FIELD OF THE INVENTION
The present invention relates to the noscapine analog 9-aminonoscapine, pharmaceutical compositions incorporating 9-aminonoscapine analog, and methods of using the compound and compositions to treat cancers, including drug resistant cancers.
BACKGROUND OF THE
9-aminonoscapine and its use in treating cancers, including drug-resistant cancers
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FIELD OF THE INVENTION
The present invention relates to the noscapine analog 9-aminonoscapine, pharmaceutical compositions incorporating 9-aminonoscapine analog, and methods of using the compound and compositions to treat cancers, including drug resistant cancers.
BACKGROUND OF THE
Noscapine derivatives as adjuvant compositions and methods of use thereof
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FIELD OF THE INVENTION
The present invention relates to an adjuvant composition comprising noscapine and its derivatives, for use in the treatment of tumors, cancer, as an adjuvant for vaccines.
BACKGROUND
Some antigens are highly immunogenic and are capable alone of eliciting protective immune
Noscapine and noscapine derivatives, useful as anticancer agents
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BACKGROUND OF THE INVENTION
Two important events in the cell division cycle are the duplication of the chromosomal DNA and the separation of the duplicated chromosomes. These events occur in two discrete phases: the synthetic phase (S-phase) and the mitotic phase (M-phase), which are separated from
Delivery systems and methods for noscapine and noscapine derivatives, useful as anticancer agents
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to delivery systems and methods useful for the treatment of neoplastic diseases, and to combinations of treatments useful for the treatment of neoplastic diseases.
2. Description of Related Art
Two important events
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