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paris/hypoxia

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Extract of Paris polyphylla Simth protects cardiomyocytes from anoxia-reoxia injury through inhibition of calcium overload.

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OBJECTIVE To assess any direct effect of extract of Paris polyphylla Simth (EPPS), a Chinese plant, on a cardiomyocyte subject to ischemia-reperfusion injury and to further elucidate its protective effect against myocardium ischemia on the cellular level. METHODS Neonatal rat cardiomyocytes were
OBJECTIVE This study sought to determine the risk factors for short term mortality in the victims of the heat wave of August 2003 in France from among patients evaluated in our emergency department (ED). It was hypothesised that age, temperature, and some long term therapies and pre-existing

Hypoxemia Index Associated with Prehospital Intubation in COVID-19 Patients

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Background: There exists a need for prognostic tools for the early identification of COVID-19 patients requiring prehospital intubation. Here we investigated the association between a prehospital Hypoxemia Index (HI) and the need for

Nitrous oxide emissions from denitrifying activated sludge of urban wastewater treatment plants, under anoxia and low oxygenation.

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Batch experiments were made to better understand the mechanisms of N2O emissions from activated sludge in denitrifying conditions found in urban WWTPs, i.e. under anoxic and low oxygenation conditions. The results showed that in completely anoxic conditions, denitrification, related to a periplasmic

Naloxone: effects on hypoxic pulmonary vasoconstriction.

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To determine the effect of naloxone on the hypoxic pulmonary vasoconstrictive response, six mongrel dogs were rendered hypoxic with 10% oxygen and were given either saline or naloxone. Following hypoxia all dogs had significant increases in mean pulmonary artery pressure (PAP) and pulmonary arterial

[Collateral circulations and new vessels in retinal branch vein occlusions. II. New vessels (author's transl)].

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Two types of anastomotic new vessels develop after retinal branch vein occlusions. In a previous article (Arch. Ophtal. (Paris), 1977, 8-9, pp. 507-522) the useful collateral vessels were described in the re-establishment of a better circulation in the territory of the occluded vein. The second part

Polyphyllin D exerts potent anti-tumour effects on Lewis cancer cells under hypoxic conditions.

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Paris polyphylla has been used to treat cancer in China for many years and components of the plant, such as polyphyllin D, may have potent antiproliferative effects in vitro. To investigate the potential antitumour effects of polyphyllin D on cancer cells under hypoxia, Lewis lung cancer cells and

[Poisoning with "poppers", a rare cause of methemoglobinemia observed in emergency cases].

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BACKGROUND Methemoglobulinemia should be entertained as a differential diagnosis in patients with cyanosis. Recently in France there has been an increase in the number of cases of acquired methemoglobulinemia due to inhalation of poppers. METHODS Four patients were admitted to the emergency room of

On the distribution of nonrighthandedness among twins and their families.

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In 773 three-generation families of twins, individual probability of nonrighthandedness (NRH) depends significantly on the handedness of that individual's parents. The parents of twins are much more often NRH than are their nontwinbearing siblings. The twins and their siblings apparently inherit the

[Mycoplasma pneumoniae, community-acquired pneumonia and asthma].

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Mycoplasma pneumoniae is an intracellular pathogen, devoid of cell wall, able to invade airway epithelial cells. Infection may either remain asymptomatic or induce bronchitis and pneumonia. M. pneumoniae is the first-ranking aetiological agent of community-acquired pneumonias in children over five

[Link between non hypoxemic chronic obstructive pulmonary disease and executive functioning in oldest old].

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COPD (chronic obstructive pulmonary disease) may result in cognitive disorders (mainly executive) even without hypoxemia. The aim of this descriptive study was to highlight a deficit in task-switching in non-hypoxemic patient with COPD and mild cognitive impairment (MCI) or Alzheimer disease (AD).

Acute chest syndrome after laparoscopic splenectomy in children with sickle cell disease: operative time dependent?

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BACKGROUND Laparoscopic splenectomy remains a technically demanding procedure. On patients with sickle cell disease (SCD), a post operative acute chest syndrome (ACS) can occur. The aim of the study was to look for predictive factors of post operative ACS. METHODS It's a retrospective study on

[Sickle cell trait complications: A case series of 6 patients]

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Introduction: Patients with sickle cell trait (SCT) are commonly considered as asymptomatic carriers. However, some clinical manifestations may occur. Methods: Here we present

Inhibition of ZNF746 suppresses invasion and epithelial to mesenchymal transition in H460 non-small cell lung cancer cells.

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Although ZNF746, also known as Parkin-interacting substrate (PARIS), has been reported to suppress peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and its target gene NRF-1 leading to the neurodegeneration in Parkinson's disease, its function in tumorigenesis has yet to be

Trajectories of river chemical quality issues over the Longue Durée: the Seine River (1900S-2010).

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River quality trajectories are presented for (i) organic pollution, (ii) eutrophication, (iii) nitrate pollution, and (iv) metal contamination over the Longue Durée (130 to 70 years). They are defined by a quantified state indicator (S) specific to each issue, compared to drivers (D) or pressures
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