The present invention relates to a uridine diphosphate (UDP)-glycosyltransferase protein which has glycosylation activity for a hydroxyl group at the C-20 position of a protopanaxadiol (PPD)- or protopanaxatriol (PPT)-type ginsenoside, and a method for glycosylation of UDP using the same.

KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

INTELLIGENT SYNTHETIC BIOLOGY CENTER

Korea Advanced Institute of Science and Technology

Intelligent Synthetic Biology Center

Method for glycosylation of ginsenoside using a glycosyltransferase derived from panax ginseng

Disclosed herein is a whitening cosmetic composition containing plant-derived ginsenoside F1 (20-O-.beta.-D-glucopyranosyl-20(S)-protopanaxatriol) as an active ingredient. More specifically, the ginsenoside F1 is obtained from particularly a ginseng extract using an acid, a base, an enzyme or microorganism, and a whitening cosmetic composition containing the ginsenoside F1 has an excellent effect of inhibiting melanin biosynthesis, and thus provides an excellent skin whitening effect.

Park; Jun Seong

Park; Hye Yoon

Ahn; Soo Mi

Kang; Byung Young

Lee; Jin Young

Kim; Eun Joo

Kim; Duck Hee

Jang; Ih Seop

Amorepacific Corporation

Use of melanin biosynthesis inhibitors from korean ginseng and the cosmetic composition containing thereof for skin whitening

Disclosed herein is nanoemulsion prepared by emulsifying main metabolites of ginseng saponin obtained by conversion of glucose, i.e. compound K (20-O-.beta.-D-glucopyranosyl-20(S)-protopanaxadiol), ginsenoside F1 (20-O-.beta.-D-glucopyranosyl-20(S)-protopanaxatriol) and compound Y (20-O-[.alpha.-L-arabinopyranosyl(1.fwdarw.6)-.beta.-D-glucopyranosyl]-20- (S)-protopanaxadiol); and admixture thereof, in fine emulsion or liposome with dermotropic emulsifier by nano-emulsification; and having enhanced skin penetration, so to be effective in promoting proliferation of fibroblast and biosynthesis of collagen.

Nanoemulsion comprising metabolites of ginseng saponin as an active component and a method for preparing the same, and a skin-care composition for anti-aging containing the same