quillaic acid/cáncer

El enlace se guarda en el portapapeles.

ArtículosEnsayos clínicosPatentes

Elija el tipo de clasificación

10 resultados

In vitro evaluation and molecular docking of QS-21 and quillaic acid from Quillaja saponaria Molina as gastric cancer agents

Solo los usuarios registrados pueden traducir artículos

Iniciar sesión Registrarse

The cytotoxic mechanism of the saponin QS-21 and its aglycone quillaic acid (QA) was studied on human gastric cancer cells (SNU1 and KATO III). Both compounds showed in vitro cytotoxic activity with IC₅₀ values: 7.1 μM (QS-21) and 13.6 μM (QA) on SNU1 cells; 7.4 μM (QS-21) and 67 μM (QA)

Antiproliferative quillaic acid and gypsogenin saponins from Saponaria officinalis L. roots.

Solo los usuarios registrados pueden traducir artículos

Iniciar sesión Registrarse

Nine quillaic acid and five gypsogenin bisdesmosides were isolated from roots of Saponaria officinalis L. (Caryophyllaceae). Seven of the quillaic acid saponins possessed a 3-O-β-D-galactopyranosyl-(1 → 2)-[β-D-xylopyranosyl-(1 → 3)]-β-D-glucuronopyranosyl unit, but differed from each other in

Saponins-mediated potentiation of cisplatin accumulation and cytotoxicity in human colon cancer cells.

Solo los usuarios registrados pueden traducir artículos

Iniciar sesión Registrarse

The triterpene saponins jenisseensosides A, B, C, D were found to increase the accumulation and cytotoxicity of the anticancer agent cisplatin in human colon tumor cells. These compounds are glycosides of quillaic acid whose fucose residue was acylated by a trans- or cis-p methoxycinnamic acid. In

A triterpenoid saponin from Adenophora triphylla var. japonica suppresses the growth of human gastric cancer cells via regulation of apoptosis and autophagy.

Solo los usuarios registrados pueden traducir artículos

Iniciar sesión Registrarse

In the present study, we investigated the effects of 3-O-β-D-galactopyranosyl-(1 → 2)-[β-D-xylopyranosyl-(1 → 3)]-β-D-glucuronopyranosyl-28-O-[α-L-arabinopyranosyl-(1 → 4)-α-L-arabinopyranosyl-(1 → 3)-β-D-xylopyranosyl-(1 → 4)-α-L-rhamnopyranosyl-(1 → 2)-β-D-fucopyranosyl] quillaic acid, named

New acylated triterpene saponins from Silene fortunei that modulate lymphocyte proliferation.

Solo los usuarios registrados pueden traducir artículos

Iniciar sesión Registrarse

Three new acylated triterpene saponins 1-3, with a quillaic acid as aglycon, were isolated from the roots of Silene fortunei together with a known phytoecdysteroid (20-hydroxyecdysone). The compounds were characterized mainly by a combination of 2D NMR techniques, mass spectrometry, and chemical

Two new triterpenoids from Gypsophila oldhamiana.

Solo los usuarios registrados pueden traducir artículos

Iniciar sesión Registrarse

Two new triterpenoids (1-2) were isolated and elucidated from the roots of Gypsophila oldhamiana, together with four known triterpenoids (3-6). Their structures were identified to be 3β-hydroxyolean-13(18)-ene-23, 28-dioic acid (1), 3β, 12α-dihydroxy-23-carboxyolean-28, 13β-olide (2), 3β,

A major triterpenoid saponin from Gypsophila oldhamiana.

Solo los usuarios registrados pueden traducir artículos

Iniciar sesión Registrarse

A new saponin, gypoldoside A (1), was isolated from the roots of Gypsophila oldhamiana. On the basis of in-depth NMR-spectroscopic and mass-spectrometric analysis, in combination with chemical evidence, its structure was established as

The Effects of Triterpenoid Saponins from the Seeds of Momordica cochinchinensis on Adipocyte Differentiation and Mature Adipocyte Inflammation

Solo los usuarios registrados pueden traducir artículos

Iniciar sesión Registrarse

Obesity is a medical condition in which abnormal or excessive fat accumulates to an extent that is associated with various diseases. In our ongoing research to figure out natural products with anti-obesity effects, a phytochemical investigation of the EtOH extract of the seeds of Momordica

Structure-activity relationships of saponins enhancing the cytotoxicity of ribosome-inactivating proteins type I (RIP-I).
Solo los usuarios registrados pueden traducir artículos
Iniciar sesión Registrarse

Saponins are amphiphilic secondary plant compounds able to interfere with surfaces and permeabilize membranes. In addition to antimicrobial and anti-inflammatory features, anti-neoplastic activities are described which base on various mechanisms. A very promising anti-cancer strategy is the

Cytotoxic effects of four Caryophyllaceae species extracts on macrophage cell lines.
Solo los usuarios registrados pueden traducir artículos
Iniciar sesión Registrarse

BACKGROUND Saponins have been reported to possess antitumor properties, to inhibit angiogenesis and to induce tumor apoptosis. OBJECTIVE To test the possible cytotoxic effect of crude extracts from four Caryophyllaceae species including Gypsophila paniculata L., Gypsophila trichotoma Wend.,

Únete a nuestra
página de facebook
Herbal & Natural Medicine
La base de datos de hierbas medicinales más completa respaldada por la ciencia
Funciona en 55 idiomas
Curas a base de hierbas respaldadas por la ciencia
Reconocimiento de hierbas por imagen
Mapa GPS interactivo: etiquete hierbas en la ubicación (próximamente)
Leer publicaciones científicas relacionadas con su búsqueda
Buscar hierbas medicinales por sus efectos.
Organice sus intereses y manténgase al día con las noticias de investigación, ensayos clínicos y patentes.
Escriba un síntoma o una enfermedad y lea acerca de las hierbas que podrían ayudar, escriba una hierba y vea las enfermedades y los síntomas contra los que se usa.
* Toda la información se basa en investigaciones científicas publicadas.