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quinovic acid/mitragyna
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[Quinovic acid triterpenoid saponins from bark of Mitragyna rotundifolia].
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OBJECTIVE
To study the chemical constituents from the bark of Mitragyna rotundifolia.
METHODS
Column chromatographic techniques were applied to isolate constituents. A combination of IR, MS and NMR spectroscopy was used to identify structures of constituents.
RESULTS
Six compounds were isolated from
Quinovic acid glycosides from Mitragyna stipulosa--first examples of natural inhibitors of snake venom phosphodiesterase I.
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Phytochemical investigations on the non-alkaloidal extracts of Mitragyna stipulosa bark has led to the isolation of a series of triterpenoids mainly consisting of quinovic acid ([structure: see text]) and its glycoside derivatives [structure: see text] and [structure: see text]. The other
27-Nor-triterpenoid glycosides from Mitragyna inermis.
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From the bark of Mitragyna inermis, two 27-nor-triterpenoid glycosides, named inermiside I (1) and II (2), were isolated and their structures determined based on extensive 2D-NMR and MS spectral analysis as
[Triterpenoid saponins from bark Mitragyna inermis].
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OBJECTIVE
To study the constituents of Mitragyna inermis that have an anti-tumor activity on Bel-7402 of hepatic carcinoma.
METHODS
The compounds were isolated by column chromatography on silica gel, ODS, Sephadex LH-20 separately and their structures were elucidated by chemical and spectral
Structure-activity relationship of triterpenoids isolated from Mitragyna stipulosa on cytotoxicity.
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Chromatographic separation of the stem bark extract of Mitragyna stipulosa afforded triterpene derivatives ursolic acid (1), quinovic acid (2), quinivic acid 3-O-beta-D-glucopyranoside (3, quinovin glycoside C), quinovic acid 3-O-[(2-O-sulfo)-beta-D-quinovopyranoside] (4, zygophyloside D) and
Phytochemical characterization of the leaves of Mitragyna speciosa grown in U.S.A.
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Mitragyna speciosa (Rubiaceae) has traditionally been used in the tropical regions of Asia, Africa and Indonesia as a substitute for opium. Indole alkaloids are the most common compounds that have been isolated. We investigated the constituents of the leaves of M. speciosa that was grown at the
A new 9-methoxyyohimbine-type indole alkaloid from Mitragyna africanus.
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A new yohimbine-type indole alkaloid (1). was isolated from the stem bark of Mitragyna africanus (WILLD.) collected in Nigeria, along with known seven Corynanthe-type oxindole alkaloids, two secoiridoids, three lignans, and a quinovic acid derivative. Their structures were elucidated by
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