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New cytotoxic triterpenoid saponins from the whole plant of Clematis lasiandra Maxim.
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Four new oleanane type triterpenoid saponins (1-4) and three known saponins (5-7) were isolated from the whole plant of Clematis lasiandra Maxim. The structures of the four new compounds were elucidated as 3-O-β-D-ribopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-[β-D-glucopyranosyl-(1 →
Cytotoxic spirostane-type saponins from the roots of Chlorophytum borivilianum.
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Four new spirostane-type saponins named borivilianosides E-H (1-4) were isolated from an ethanol extract of the roots of Chlorophytum borivilianum together with two known steroid saponins (5 and 6). The structures of 1-4 were elucidated using mainly 2D NMR spectroscopic techniques and mass
Antitumor activity of Pulsatilla koreana saponins and their structure-activity relationship.
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Seventeen saponins isolated from the root of Pulsatilla koreana were examined for their in vitro cytotoxic activity against the human solid cancer cell lines, A-549, SK-OV-3, SK-MEL-2, and HCT15, using the SRB assay method, and their in vivo antitumor activity using BDF1 mice bearing Lewis lung
Triterpenoid saponins from the roots of Clematis argentilucida and their cytotoxic activity.
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The reinvestigation of the n-BuOH extract of the roots of Clematis argentilucida led to the isolation of four new oleanane-type triterpenoid saponins, 1-4, four known saponins, 5-8, first isolated from the species, together with ten saponins, 9-18, reported in the preceding papers. The structures of
Four new furostanol saponins from the rhizomes and roots of Smilax scobinicaulis and their cytotoxicity.
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Four new furostanol saponins 1-4, along with two known furostanol saponins 5 and 6 and one known spirostanol saponin 7 were isolated from the rhizomes and roots of Smilax scobinicaulis. The structures of the new saponins were elucidated as
Studies on cytotoxic triterpene saponins from the leaves of Aralia elata.
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Aralia elata has long been used as a tonic, anticancer and antidiabetic agent in China and Japan, and is widely consumed as food. Phytochemical investigation of the leaves of A. elata has led to the isolation of four new compounds, 3-O-[β-D-glucopyranosyl(1 → 3)-β-D-glucopyranosyl] echinocystic acid
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