natural product Arabic gum (acacia gum) prepared as a mouthwash

natural product Licorice (Glycyrrhiza Glabra) root extract prepared as a mouthwash

chemical agent Chlorhexidine as a mouthwash

High Caries Risk Patients

Caries

Antimicrobial Effect

Side Effect

natural gum of acacia tree: Antimicrobial, anti-inflammatory medicinal plant used as a traditional oral hygiene substance (anticariogenic). It is used in treating sore throats, colds, bronchitis, toothache, gingival bleeding and mouth ulcers.

Arabic, Gum

natural licorice, herbal plant to relieve coughs, sore throats, and gastric inflammation. flavouring and sweetening agent. it's anti-caries, soothing anti-inflammatory and anticancer properties benefit against oral diseases and dental caries

Licorice Root

chemical agent used as a mouthwash against cariogenic bacteria. considered the gold standard

Chlorhexidine

Faculty of Dentistry Cairo University

Caries Prevention and Side Effects of Gum Arabic and Licorice Extracts Versus Chlorhexidine in High Caries Risk Patients

Effect of Gum Arabic (Acacia Gum) and Licorice (Glycyrrhiza Glabra) Mouthwashes Compared to Chlorhexidine Mouthwash on Caries Prevention and the Prevalence of Oral Side Effects in High Caries Risk Patients: A Randomized Controlled Clinical Trial

development of new caries lesions. Clinical examination during study time to Measure DMF scoring index: any changes in number of decayed, missing and filled surfaces due to caries from baseline. Done according to International Caries Detection and Assessment System (ICDAS II criteria)

Antimicrobial effect against streptococcus mutans and lactocbacilli: saliva samples collected and total bacterial count measured after agar plates incubating, expressed in colony forming units

side effects from long term use of mouthwash

Dina Mohamed Kamal Eldin

Assistant lecturer

Cairo University

Subjects were randomly allocated to a group and entered a 4-week "washout period" during which no gum was chewed, followed by a 3-week treatment period (treatment period 1) during which Group A used Xylitol gum.(2 gum pieces, 3 times daily after meals for 6 minutes).Then underwent another 4-week washout period before entering treatment period 2 during which Group A used Gum Sorbitol

Subjects were randomly allocated to a group and entered a 4-week "washout period" during which no gum was chewed, followed by a 3-week treatment period (treatment period 1) during which Group B used sorbitol gum. Group B used Gum Sorbitol (2 gum pieces, 3 times daily after meals for 6 minutes).Then underwent another 4-week washout period before entering treatment period 2 during which Group B used Gum xylitol

Human Microbiome

Xylitol gum contains 70% xylitol in addition to gum base, natural flavors, soy lecithin, gum arabic, titanium dioxide, carnuba wax. Sorbitol gum was similar except that xylitol was replaced by 63% sorbitol and 2% maltitol and aspartame was included.

Xylitol then Sorbitol gum

Sorbitol gum was similar except that xylitol was replaced by 63% sorbitol and 2% maltitol and aspartame was included. Xylitol gum contains 70% xylitol in addition to gum base, natural flavors, soy lecithin, gum arabic, titanium dioxide, carnuba wax.

Sorbitol then Xylitol gum

Xylitol and Sorbitol Effects on the Oral Microbiome

Xylitol and Sorbitol Effects on the Microbiome of Saliva and Plaque

Profile microbial communities of saliva and plaque based high-throughput sequencing of the 16S rRNA gene.

Reisha Rafeek

Senior Lecturer

The University of The West Indies

J. Craig Venter Institute

The group contains healthy individuals with chronic periodontitis who will receive Normal Saline as placebo

The group contains healthy individuals with chronic periodontitis who will receive Nigella sativa Oil as intervention

Chronic Periodontitis

The individuals will apply 55 drops of Nigella sativa Oil on gingivae twice daily for two weeks

Nigella Sativa Oil

The individuals will apply 55 drops of Normal saline on gingivae twice daily for two weeks

Normal saline

Fatima Memorial Hospital

Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis

Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis Before and After Treatment With Nigella Sativa (Kalonji) Oil

These inflammatory marker will be measured in patients saliva again after 2 weeks. There will be reduction in their levels.

senegalia angico/dental caries

Caries Prevention and Side Effects of Gum Arabic and Licorice Extracts Versus Chlorhexidine in High Caries Risk Patients

Xylitol and Sorbitol Effects on the Oral Microbiome

Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis

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