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Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells.
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The aim of this study is to investigate the effects of theanine, a tea characteristic amino acid, on human lung cancer and leukemia cells. In the present study, we have demonstrated that theanine suppressed the in vitro and ex vivo growth of human non-small cell lung cancer A549 and leukemia K562
Improvement of idarubicin induced antitumor activity and bone marrow suppression by theanine, a component of tea.
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We have examined the effect of theanine, a specific amino acid in green tea, on idarubicin (IDA)-induced antitumor activity and toxicity. In combination with theanine, IDA (0.25 mg/kg per day x4 days, a dose that does not show antitumor activity) had significant antitumor activity in P388-bearing
Inhibition of lung tumor growth by targeting EGFR/VEGFR-Akt/NF-κB pathways with novel theanine derivatives.
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The molecularly targeted agents, including anti-VEGF or anti-EGFR monoclonal antibody and some inhibitors of EGFR tyrosine kinase, are effective in the treatment of non-small-cell lung cancer (NSCLC) to a certain extent, but the benefit for a proportion of patients is still limited. Hence, it is
Versatile and Valuable Utilization of Amidohydrolase L-Glutaminase in Pharma and Food industries: A Review.
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L-Glutaminase has versatile applications in Pharma and food industries. In pharmaceutical industry, L-Glutaminase can used as anti-oxidant and anti-cancer agent to treat Acute Lymphocytic Leukaemia (ALL). Whereas, in food industry L-Glutaminase is used for acrylamide degradation, theanine
Efficacies of tea components on doxorubicin induced antitumor activity and reversal of multidrug resistance.
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Considering of novel biochemical modulation by some foods and beverages, we have performed screening for green tea components that have enhancing effects on doxorubicin (DOX) induced antitumor activity. Components, such as caffeine, theanine, (-)-epigallocatechin gallate (EGCG) and flavonoids have
Cancer stem cells: potential target for bioactive food components.
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Cancer stem cells often have phenotypic and functional characteristics similar to normal stem cells including the properties of self-renewal and differentiation. Recent findings suggest that uncontrolled self-renewal may explain cancer relapses and may represent a critical target for cancer
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