3 resultados
We investigated the pharmacological properties and interaction domains of N-(3-aminobenzyl)-6-{4-[(3-fluorobenzyl)oxy]phenoxy} nicotinamide (YM-244769), a novel potent Na(+)/Ca(2+) exchange (NCX) inhibitor, using various NCX-transfectants and neuronal and renal cell lines. YM-244769 preferentially
We investigated the properties and interaction domains of SN-6 [2-[4-(4-nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic acid ethyl ester], a newly synthesized and selective Na(+)/Ca(2+) exchange (NCX) inhibitor. SN-6 (0.3-30 microM) inhibited preferentially intracellular Na(+)-dependent (45)Ca(2+)
Recently, we developed 2-(4- [4-nitrobenzyloxy] benzyl) thiazolidine-4-carboxylic acid ethyl ester (SN-6), a newly synthesized and selective inhibitor of Na(+)/Ca(2+) exchanger. SN-6 is a selective inhibitor for the Ca(2+) influx mode of Na(+)/Ca(2+) exchanger. And this compound attenuated