Grass Sensitisation and Allergic Rhinitis in Thai Patients
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StaatusValmis
Sponsorid
Mahidol University
Kaastöötajad
National Research Council of Thailand
KLIINILISES UURINGUS: NCT01686022
BioSeek: NCT01686022
Märksõnad
Abstraktne
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.
Kirjeldus
To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.
The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.
Kuupäevad
| Viimati kinnitatud: | 08/31/2016 |
| Esmalt esitatud: | 09/11/2012 |
| Hinnanguline registreerumine on esitatud: | 09/13/2012 |
| Esmalt postitatud: | 09/16/2012 |
| Viimane värskendus on esitatud: | 09/12/2016 |
| Viimati värskendus postitatud: | 09/13/2016 |
| Õppe tegelik alguskuupäev: | 09/30/2012 |
| Eeldatav esmane lõpetamise kuupäev: | 09/30/2015 |
| Eeldatav uuringu lõpetamise kuupäev: | 09/30/2015 |
Seisund või haigus
Allergy to Grass Pollen
Allergic Rhinitis Due to Weed Pollens
Sekkumine / ravi
Other: Pollen Allergy
Faas
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Käerühmad
| Arm | Sekkumine / ravi |
|---|---|
| Pollen Allergy Pollen allergy and control will have the same intervention, ie. Skin prick test and collect serum samples.Then measure the specificIgE, immunoblot, and ELISA inhibition | Other: Pollen Allergy serum specific IgE binds to grass extract by immunoblot |
Abikõlblikkuse kriteeriumid
| Õppimiseks sobivad vanused | 10 Years To 10 Years |
| Uuringuks kõlblikud sood | All |
| Proovivõtumeetod | Non-Probability Sample |
| Võtab vastu tervislikke vabatahtlikke | Jah |
| Kriteeriumid | Inclusion Criteria: - Allergic rhinitis patients age 10-50 years old - Control: healthy volunteer age 18-50 years old Exclusion Criteria: - Chronic illness such as cardiovascular diseases, liver diseases - History of anaphylaxis - Pregnancy |
