Metabolic Effects of Short Term Sugarcane Bagasse Supplementation
Märksõnad
Abstraktne
Kirjeldus
The investigators will employ a double-blind randomized controlled study design with 3 arms such that obese, insulin resistant adults will be randomly selected to receive food made with 1) sugarcane bagasse, 2) non-caloric, non-fermentable fiber, or 3) a similar product with minimal fiber for 4 weeks. The intervention will be in the form of brownies and cookies and will look and taste nearly identical to each other. Caloric value will be constant with all three delivery systems. Subjects will have blood testing and body composition analysis before and after the intervention.
Kuupäevad
| Viimati kinnitatud: | 01/31/2016 |
| Esmalt esitatud: | 04/09/2013 |
| Hinnanguline registreerumine on esitatud: | 04/09/2013 |
| Esmalt postitatud: | 04/11/2013 |
| Viimane värskendus on esitatud: | 01/31/2016 |
| Viimati värskendus postitatud: | 02/02/2016 |
| Õppe tegelik alguskuupäev: | 03/31/2013 |
| Eeldatav esmane lõpetamise kuupäev: | 12/31/2013 |
| Eeldatav uuringu lõpetamise kuupäev: | 11/30/2014 |
Seisund või haigus
Sekkumine / ravi
Other: Sugarcane bagasse
Other: Non-caloric, non-fermentable fiber
Other: Minimal fiber
Faas
Käerühmad
| Arm | Sekkumine / ravi |
|---|---|
| Experimental: Sugarcane bagasse 10 subjects will consume food (brownies and cookies) made with 13 g of sugarcane bagasse everyday for 4 weeks | Other: Sugarcane bagasse One brownie containing 10 g of sugarcane bagasse and 2 cookies containing 3 g of sugarcane bagasse (total of 13 g of sugarcane bagasse per day) |
| Active Comparator: Non-caloric, non-fermentable fiber 10 subjects will consume food (brownies and cookies) made with 13 g of non caloric, non-fermentable fiber everyday for 4 weeks | Other: Non-caloric, non-fermentable fiber One brownie containing 10 g of fiber and 2 cookies containing 3 g of fiber (total of 13 g of non-caloric, non-fermentable fiber per day) |
| Placebo Comparator: Minimal fiber 10 subjects will consume food (brownies and cookies) made with 4 g of dietary fiber everyday for 4 weeks | Other: Minimal fiber One brownie containing 3g of fiber and two cookies containing 1g of fiber (total of 4 g of dietary fiber per day) |
Abikõlblikkuse kriteeriumid
| Õppimiseks sobivad vanused | 18 Years To 18 Years |
| Uuringuks kõlblikud sood | All |
| Võtab vastu tervislikke vabatahtlikke | Jah |
| Kriteeriumid | Inclusion Criteria: - Males and females age 18-50 years - Body Mass Index ≥ 30 kg/m2 (a ratio of weight to height) - Fasting insulin level >5 µIU/mL, as determined by tests performed during screening Exclusion Criteria: - Women who are pregnant - Past medical history of diabetes - History of intestinal surgery such as removal of bowel - History of problems with absorbing food such as celiac disease, inflammatory bowel disease, malabsorption syndrome - Taking chronic medications for any medical conditions such as diabetes, hypertension, cholesterol, thyroid hormone, etc. - Any food allergies |
Tulemus
Esmased tulemusnäitajad
1. The benefit of sugarcane bagasse on glucose tolerance and insulin resistance in adults with established insulin resistance [4 weeks]
Sekundaarsed tulemusmõõdud
1. The effect of sugarcane bagasse on body weight/composition [4 weeks]
Muud tulemusmeetmed
1. The effect of sugarcane bagasse on incretin profiles as a mechanism to explain its metabolic effects [4 Weeks]
