The Effect of Berry Extract on Helicobacter Pylori Eradication
Märksõnad
Abstraktne
Kirjeldus
One-week of triple therapy composed of a proton pump inhibitor plus two antibiotics is currently regarded as the gold standard for HP eradication. However, the eradication rate continues to be disappointing. Poor patient compliance and bacterial resistance are the main factors contributing to treatment failure. Therefore, it is urgently necessary to develop a non-antibiotic alternative therapy to increase the eradication rates of Helicobacter pylori. Some literatures reported that cranberry may inhibit Helicobacter pylori adhesion to the human gastric mucus and may reduce Helicobacter pylori infection in adults. The aims of his experiment were to explore the impact of berry extract on triple therapy for Helicobacter pylori eradication.
Kuupäevad
Viimati kinnitatud: | 12/31/2009 |
Esmalt esitatud: | 12/28/2009 |
Hinnanguline registreerumine on esitatud: | 01/07/2010 |
Esmalt postitatud: | 01/10/2010 |
Viimane värskendus on esitatud: | 01/12/2010 |
Viimati värskendus postitatud: | 01/13/2010 |
Õppe tegelik alguskuupäev: | 12/31/2008 |
Eeldatav esmane lõpetamise kuupäev: | 11/30/2009 |
Eeldatav uuringu lõpetamise kuupäev: | 05/31/2010 |
Seisund või haigus
Sekkumine / ravi
Dietary Supplement: Berry extract
Faas
Käerühmad
Arm | Sekkumine / ravi |
---|---|
Placebo Comparator: Berry | |
Placebo Comparator: Placebo |
Abikõlblikkuse kriteeriumid
Õppimiseks sobivad vanused | 18 Years To 18 Years |
Uuringuks kõlblikud sood | All |
Võtab vastu tervislikke vabatahtlikke | Jah |
Kriteeriumid | Inclusion Criteria: - Patients older than 18 Exclusion Criteria: - Pregnancy or breastfeeding - Use of antibiotics 2 weeks prior to inclusion - Previous eradication treatment |
Tulemus
Esmased tulemusnäitajad
1. Eradication rate [4 weeks after Eradication of Helicobacter pylori]