Isthmocele After Endometrial and Non-endometrial Suturing in Cesarean Section
Märksõnad
Abstraktne
Kirjeldus
Cesarean section is the most common surgery performed on pregnant women. Poor healing of the incision of the uterus leads to isthmocele development. Long-term morbidities associated with isthmocele are uterine scar pregnancy, uterine perforation, pelvic pain, and spotting-style bleeding after menstruation. Many factors that may affect the healing of uterine scar have been studied in the literature (i.e. Double or single-layer closure, locked or unlocked closure, uterine retroflection). Suturing complete fold of the wound lips during the closure of the uterus may cause the endometrial layer to be embedded in the myometrium and to form niche tissue. The study hypothesized that isthmocele development can be reduced by suturing without enclosing the endometrium during uterine closure.
Kuupäevad
| Viimati kinnitatud: | 11/30/2019 |
| Esmalt esitatud: | 12/11/2019 |
| Hinnanguline registreerumine on esitatud: | 12/11/2019 |
| Esmalt postitatud: | 12/12/2019 |
| Viimane värskendus on esitatud: | 12/15/2019 |
| Viimati värskendus postitatud: | 12/16/2019 |
| Õppe tegelik alguskuupäev: | 12/15/2019 |
| Eeldatav esmane lõpetamise kuupäev: | 11/30/2020 |
| Eeldatav uuringu lõpetamise kuupäev: | 11/30/2020 |
Seisund või haigus
Sekkumine / ravi
Procedure: Entire fold uterine closure
Procedure: Non-endometrial uterine closure
Faas
Käerühmad
| Arm | Sekkumine / ravi |
|---|---|
| Active Comparator: Entire fold uterine closure The uterus will be sewn with full fold locked sutures that pass through myometrium and endometrium. | Procedure: Entire fold uterine closure Closure of the uterus at the time of primary cesarean will be performed with suturing the endometrium. |
| Experimental: Non-endometrial uterine closure The uterus will be sewn with locked sutures that pass through myometrium without endometrium. | Procedure: Non-endometrial uterine closure Closure of the uterus at the time of primary cesarean will be performed without suturing the endometrium. |
Abikõlblikkuse kriteeriumid
| Õppimiseks sobivad vanused | 18 Years To 18 Years |
| Uuringuks kõlblikud sood | Female |
| Võtab vastu tervislikke vabatahtlikke | Jah |
| Kriteeriumid | Inclusion Criteria: - Term pregnancy (≥37 weeks of gestation) - Singleton pregnancy - Primary cesarean Exclusion Criteria: - Previous cesarean section - Previous uterine surgery - Multiple gestations - Mullerian anomalies - Active labor - Placenta previa/accreta |
Tulemus
Esmased tulemusnäitajad
1. Number of patients with isthmocele six month after cesarean section [6 months after intervention]
2. Mean myometrium thickness [6 months after intervention]
Sekundaarsed tulemusmõõdud
1. Spotting [6 months after intervention]
