Use of PRP in Endometrial Reconstruction
Märksõnad
Abstraktne
Kirjeldus
The objective is to know the effect of these regenerative factors obtained from Platelet-Rich Plasma in an immunodeficient murine model with AS/EA Blood from patients with Asherman's Syndrome (AS) and Endometrial Atrophy (EA) will be collected, maintained under anticoagulant solution and after several centrifugations PRP will be obtained. Demonstration of a functional endometrium will be proved determining pregnancy and implantation rates as well as the number of live pups/pregnant female in our mice model. Also, the uterus histology will be analysed in treated and untreated mice
Kuupäevad
Viimati kinnitatud: | 04/30/2020 |
Esmalt esitatud: | 06/07/2017 |
Hinnanguline registreerumine on esitatud: | 08/13/2017 |
Esmalt postitatud: | 08/14/2017 |
Viimane värskendus on esitatud: | 05/13/2020 |
Viimati värskendus postitatud: | 05/14/2020 |
Õppe tegelik alguskuupäev: | 07/17/2017 |
Eeldatav esmane lõpetamise kuupäev: | 11/30/2020 |
Eeldatav uuringu lõpetamise kuupäev: | 11/30/2020 |
Seisund või haigus
Faas
Abikõlblikkuse kriteeriumid
Õppimiseks sobivad vanused | 25 Years To 25 Years |
Uuringuks kõlblikud sood | Female |
Proovivõtumeetod | Probability Sample |
Võtab vastu tervislikke vabatahtlikke | Jah |
Kriteeriumid | Inclusion Criteria: - Participants diagnosed with Asherman Syndrome and Endometrial Atrophy by Hysteroscopy. - No pregnancy after hormonal treatment. Exclusion Criteria: - Psychiatric diseases. |
Tulemus
Esmased tulemusnäitajad
1. Endometrial thickness after reconstruction in murine model [through study completion, an average of 1 year]