Effect of hypergravity and hyperthermia on antidiuretic hormone secretion.

The effect of acceleration and hyperthermia on the antidiuretic hormone secretion (ADH) was investigated in rats both separately and simultaneously. The two conditions of stress elicited a rise in plasma ADH concentration in proportion to their intensity. Concomitant exposure to the two factors produced an additional effect. The parallel histochemical studies using methods for demonstrating RNA, proteins and the neurosecretory material in the supraoptic nucleus, showed the synthesis and depletion of the hormone content in correlation with the plasma concentration of ADH.