allyl alcohol/maksapõletik

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[Morphofunctional status of blood and bone marrow cells in acute experimental hepatitis induced by allyl alcohol].

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Acute experimental hepatitis was induced by a single injection of 1% water solution of allyl spirit in a dose of 100 mg/kg. Morphofunctional state of peripheral blood and bone marrow cells was studied with the use of hematological and cytochemical methods. Specific changes were detected in the

[Effect of perftoran on experimental hepatitis].

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The effect of perftoran on the course of experimental acute hepatitis in albino rats was studied on the hepatitis models induced by allyl alcohol or P. acnes culture with typhoid fever endotoxin. Perftoran (10 ml/kg) favored more rapid cytolytic syndrome elimination by affecting the lipid

A novel biologically active seleno-organic compound--VI. Protection by ebselen (PZ 51) against galactosamine/endotoxin-induced hepatitis in mice.

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Male albino NMRI mice were given 700 mg/kg galactosamine and 33 micrograms/kg salmonella endotoxin intraperitoneally. After 9 hr, serum sorbitol dehydrogenase activity had risen from 60 to 7320 U/l, SGOT from 90 to 5580, and SGPT from 70 to 10,440. When a similar dose of galactosamine alone or

Measurement of in vivo lipid peroxidation and toxicological significance.

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The quantitative determination of hydrocarbons exhaled by animals as an in vivo index of extensive lipid peroxidation is described. Advantages and limitations of this method are discussed. Acetaminophen-induced hepatic lipid peroxidation in mice is an example of oxidative stress, the extent of which

Neoductular progenitor cells regenerate hepatocytes in severely damaged liver: a comparative ultrastructural study.

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In severely injured liver, stem cells give rise to progeny that tend to replace lost hepatocytes. Neoductular reaction appears as an inherent stage of liver reconstruction following severe damage caused by different pathological mechanisms. Few ultrastructural types of progenitor cells have been

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