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aortic valve insufficiency/phosphatase

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ArtiklidKliinilistes uuringutesPatendid
10 tulemused

Myofibrillar and actomyosin adenosine-tri-phosphatase in experimental aortic insufficiency.

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Logi sisse
OBJECTIVE To investigate the effects of valsartan on expressions of myocardial sarcoplasmic reticulum calcium adenosine triphosphatase (SERCA2), protein kinase A (PKA) and protein phosphatase 1 alpha (PP1alpha) in a rabbit model of heart failure. METHODS Rabbits were divided into sham-operated

I-cell disease: report of an autopsy case.

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Logi sisse
The history and findings at autopsy of a 9-year-old female with I-cell disease are reported. She manifested gargoyle face, progressive psychomotor retardation, and increased serum levels of lysosomal enzymes with decreased activities in peripheral blood lymphocytes. She received a bone marrow

Effect of treatment with alendronate in osteogenesis imperfecta type I: a case report.

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Logi sisse
A case of osteogenesis imperfecta (OI), which was successfully treated with alendronate is reported. A 41-year-old premenopausal woman with OI type I, who had frequently been experiencing fragile fractures, consulted our clinic because of back pain associated with spinal osteoporosis. She had

Simvastatin does not diminish the in vivo degeneration of decellularized aortic conduits.

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Logi sisse
BACKGROUND All present biological cardiovascular prostheses are prone to progressive in vivo degeneration, which can be partially impaired by decellularization. The administration of statins may provide an additional beneficial effect. We provide the first in vivo data on the effect of statins on

Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.

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BACKGROUND AND PURPOSE
Calcification of heart valves is a frequent pathological finding in chronic kidney disease and in elderly patients. Hydrogen sulfide (H2 S) may exert anti-calcific actions. Here we investigated H2 S as an inhibitor of valvular
Warfarin, a vitamin K antagonist, is the most common anticoagulant used to prevent thromboembolisms associated with atrial fibrillation or following valvular surgery. Although several studies have revealed that long-term warfarin use accelerates aortic valve calcification and the development of
Calcific aortic valve stenosis (CAS) is the most frequent heart valve disease in the elderly, accompanied by valve calcification. Tumor necrosis factor-α (TNF-α), a pleiotropic cytokine secreted mainly from macrophages, has been detected in human calcified valves. However, the role of TNF-α in valve

Aortic and mitral valve disease in patients with end stage renal failure on long-term haemodialysis.

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Logi sisse
OBJECTIVE To identify valvar heart disease in patients with chronic uraemia by conventional and colour coded Doppler echocardiography. METHODS Case series of an unselected group of 62 patients with end stage renal failure. METHODS Centre for haemodialysis in a referral hospital in

Altered microRNAs in bicuspid aortic valve: a comparison between stenotic and insufficient valves.

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Logi sisse
OBJECTIVE Bicuspid aortic valve (BAV), the most common form of congenital heart disease, is a leading cause of aortic stenosis (AS) and aortic insufficiency (AI). AS is typically caused by calcific valve disease. Recently, microRNAs (miRNAs) have been shown to modulate gene expression. The study aim
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