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Acridone alkaloids, cycloatalaphylline-A (1), N-methylcyclo-atalaphylline-A (2) and N-methylbuxifoliadine-E (3), were isolated from the dichloromethane and acetone extracts of the root of Atalantia monophylla along with eight known acridone alkaloids: buxifoliadine-A (4), buxifoliadine-E (5),
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The leaves of ATALANTIA CEYLANICA have yielded four compounds including a novel benzaldehyde derivative, 2,4,5-trimethoxybenzaldehyde ( 1), and two acridone alkaloids: 1,5-dihydroxy-3-methoxy-10-methyl-9(10 H)-acridinone ( 2) and 11-hydroxynoracronycine ( 3), 2 is a new alkaloid and constitutes one
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A new furoquinoline alkaloid, 5-hydroxydictamnine, along with β-sitosterol was isolated from the heartwood of Atalantia monophylla. The structure of this alkaloid was established by chemical and spectral evidences together with a nuclear overhauser effect (NOE) experiment.
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From the dried root and rhizomes of Atalantia buxifolia afford 11 compounds, one new compound 1 and ten known compounds 2-11 were isolated and identified. The novel compound 1 was alkaloid glycoside. Its mother nuclear was the acridone, which was relatively rare.
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Eight new acridone alkaloids, buxifoliadines-A--H together with nine known acridone compounds, were isolated and characterized from the root bark of Severinia buxifolia which was collected in Hainan province, China. Their structures were determined by spectroscopic methods. The relationship between
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Two new acridone alkaloids, 3-methoxy-1,4,5-trihydroxy-10-methylacridone (1) and 2,3-dimethoxy-1,4,5-trihydroxy-10-methylacridone (2), were isolated from the ethanol extract of the branch of Atalantia buxifolia. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR.
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Seven new benzoyltyramines, atalantums A-G (1-7), and five known compounds were isolated from the peels of Atalantia monophylla. All compounds were examined for cytotoxicity against the cholangiocarcinoma cell lines KKU-M214, KKU-M213, and KKU-M156. Compound 5 exhibited the strongest cytotoxicity
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Study of the chemical constituents of ethanol extract from the aerial parts of Atalantia buxifolia led to the identification of a new acridone alkaloid named as buxifoliadine (1), along with known compounds citrusinine--I (2), N-methylatalaphylline (3), Severinolid (4) and cycloseverinolide (5).
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Three new limonoids, limonophyllines A-C (1, 4 and 5), along with two known limonoids (2 and 3) and 11 acridone alkaloids (6-16) were isolated from the stems of Atalantia monophylla. All isolates were evaluated against cholangiocarcinoma, KKU-M156, and HepG2 cancer cell lines. Compounds 12, 14 and
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Phytochemical analysis of different organs of the rutaceaeous plant Severinia buxifolia led to the isolation of a new limonoid, a new acridone alkaloid, and a new flavone. Structure elucidation and signal assignment were achieved by the extensive use of 1D and 2D NMR experiments (selective 1D NOE,
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Two new tetranortriterpenoids, 7-isovaleroylcycloseverinolide (1) and 7-isovaleroylcycloepiatalantin (2), together with 28 known compounds, were isolated and characterized from the root bark of Severinia buxifolia collected in Hainan. The structures of 1 and 2 were elucidated on the basis of
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Five new compounds named buxifoximes A-C (1-3), buxifobenzoate (4), and 7- O-(7'-peroxygeranyl) coumarin (5), together with 25 known compounds, were identified from the twigs of Atalantia buxifolia. Compounds 1-3 are unique secondary metabolites with the aldoxime functionality. The structures of the
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THE TITLE ACRIDONE ALKALOID [SYSTEMATIC NAME: 1,3,5-trihydr-oxy-2,4-bis-(3-methyl-but-2-en-yl)acridin-9(10H)-one], C(23)H(25)NO(4), known as atalaphylline, was isolated from Atalantia monophylla Corrêa, a mangrove plant. The mol-ecule contains three fused planar rings with an r.m.s. deviation of
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