Leht 1 alates 16 tulemused
The present invention relates to novel benzamide inhibitors of the P2X.sub.7 receptor, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present invention are useful in the
BACKGROUND OF THE INVENTION
The present invention relates to novel benzamide inhibitors of the P2X.sub.7 receptor, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present
BACKGROUND OF THE INVENTION
The present invention relates to novel benzamide inhibitors of the P2X.sub.7 receptor, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present
The present invention relates to novel benzamide inhibitors of the P2X.sub.7 receptor, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present invention are useful in the
BACKGROUND OF THE INVENTION
The present invention relates to novel benzamide inhibitors of the P2X.sub.7 receptor, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present
BACKGROUND OF THE INVENTION
The present invention relates to novel benzamide inhibitors of the P2X.sub.7 receptor, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present
BACKGROUND OF THE INVENTION
The present invention relates to novel benzamide inhibitors of the P2X.sub.7 receptor, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present
The present invention relates to 4-fluoro-N-indan-2-yl benzamide of the formula (I) and its use as pharmaceutical agent.
##STR00002##
Endothelial NO synthase (eNOS, NOS-III) belongs to a group of three isoenzymes which produce nitric oxide (NO) by oxidation of arginine. Endothelially released NO is
The present invention relates to 4-fluoro-N-indan-2-yl benzamide of the formula (I) and its use as pharmaceutical agent. ##STR2##
Endothelial NO synthase (eNOS, NOS-III) belongs to a group of three isoenzymes which produce nitric oxide (NO) by oxidation of arginine. Endothelially released NO is of
The present invention relates to 4-fluoro-N-indan-2-yl benzamide of the formula (I) and its use as pharmaceutical agent. ##STR2##
Endothelial NO synthase (eNOS, NOS-III) belongs to a group of three isoenzymes which produce nitric oxide (NO) by oxidation of arginine. Endothelially released NO is of
The present invention relates to N-alkyl adamantyl triazinyl benzamide derivatives, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present invention are useful in the
FIELD OF THE INVENTION
The present invention relates to novel benzamide, heteroarylamide and reverse amide, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present invention
The present invention relates to novel benzamide, heteroarylamide and reverse amide, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present invention are useful in the
FIELD OF THE INVENTION
This invention provides benzoic acid and amide derivatives of anthranilic acids which inhibit certain dual specificity kinase enzymes involved in proliferative diseases such as cancer and restenosis.
BACKGROUND OF THE INVENTION
Proliferative diseases are caused by a defect in
FIELD OF THE INVENTION
This invention provides benzoic acid and amide derivatives of anthranilic acids which inhibit certain dual specificity kinase enzymes involved in proliferative diseases such as cancer and restenosis.
BACKGROUND OF THE INVENTION
Proliferative diseases are caused by a defect in