6 tulemused
Eight alkaloids, including a new compound, (+)-norboldine acetate (1), and seven known ones, (+)-norboldine (2), (+)-boldine (3), (+)-laurotetanine (4), (+)-N-methyllaurotetanine (5), (+)-reticuline (6), (-)-pronuciferine (7), and pallidine (8) were isolated from the roots of Lindera aggregata. The
Lindera angustifolia Chen is a folk medicine used for the treatment of contusions-induced swelling, rheumatic pains and bellyache in south and the middle part of China. Phytochemical studies showed that aporphine and benzyltetrahydroisoquinoline alkaloids are the characteristic constituents of this
OBJECTIVE
To study the alkaloid constituents of the root of Lindera angustifolia Cheng.
METHODS
The constituents were isolated and purified by column chromatography and the structures were characterized by spectral analysis.
RESULTS
Seven aporphine alkaloids, laurotetanine (I), N-methyllaurotetanine
To study the chemical constitutes from the roots of Lindera glauca and the alkaloids influence on proliferation of HT-29,SGC-7901,SMMC-7721 and A549 cell lines.
The constituents were isolated by column chromatography such as RP-18,Sephadex LH-20 and silica gel,and their structures were elucidated by
A new separation and quantification method using liquid chromatography under ultra-high-pressure in combination with tandem mass spectrometry (MS/MS) was developed for simultaneous determination of four alkaloids in Lindera aggregata. The analysis was performed on an Acquity UPLC BEH C(18) column
OBJECTIVE
To develop an HPLC method for simultaneous determination of four major alkaloids in Lindera aggregate.
METHODS
The analysis was carried out on an Agilent ZORBAX SB-C18 column (4.6 mm x 250 mm, 5 microm) with gradient elution using acetonitrile-water (containing 0. 15% diethylamine,