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bromophenol/nekroos
Link salvestatakse lõikelauale
11 tulemused
In vitro antiviral activity of red alga, Polysiphonia morrowii extract and its bromophenols against fish pathogenic infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus.
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Logi sisse
Our previous investigation revealed that 80% methanolic extract of the red alga Polysiphonia morrowii has significant antiviral activities against fish pathogenic viruses, infectious hematopoietic necrosis virus (IHNV) and infectious pancreatic necrosis virus (IPNV). The present study was conducted
The role of ortho-bromophenol in the nephrotoxicity of bromobenzene in rats.
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Logi sisse
ortho-Bromophenol (1.92 mmol/kg, ip) caused a 50% decrease in renal glutathione levels within 90 min. In contrast, hepatic glutathione levels remained 80% of control values 5 hr after ortho-bromophenol administration. Renal glutathione was far more susceptible to the initial rapid depleting effects
Comparative in vitro safety analysis of dyes for chromovitrectomy: indocyanine green, brilliant blue green, bromophenol blue, and infracyanine green.
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Logi sisse
OBJECTIVE
Vital dyes such as infracyanine green (IfCG), brilliant blue green (BBG), and bromophenol blue (BPB) have been used as an alternative to indocyanine green (ICG) during chromovitrectomy. We compared the in vitro toxicity of IfCG, BBG, and BPB with ICG on the retinal pigment epithelial cells
Effect of bromobenzene and O-bromophenol on kidney and liver of English sole (Parophrys vetulus).
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Logi sisse
1. English sole (Parophrys vetulus) were injected intraperitoneally with a single dose of 9.8 mmol bromobenzene/kg of fish or 1.9 mmol O-bromophenol/kg of fish, both known renal toxicants in mammals. 2. Kidney, liver, gill spleen, intestines, heart and blood samples were subsequently obtained up to
Bis (3-bromo-4,5-dihydroxybenzyl) ether, a novel bromophenol from the marine red alga Polysiphonia morrowii that suppresses LPS-induced inflammatory response by inhibiting ROS-mediated ERK signaling pathway in RAW 264.7 macrophages.
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Logi sisse
Inflammation is a pathophysiological defense response against various factors for maintaining homeostasis in the body. However, when continued excessive inflammation becomes chronic, various chronic diseases can develop. Therefore, effective treatment before chronic inflammation development is
Treatment with 3-Bromo-4,5-Dihydroxybenzaldehyde Improves Cardiac Function by Inhibiting Macrophage Infiltration in Mice.
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Logi sisse
OBJECTIVE
Appropriate inflammatory response is necessary for cardiac repairing after acute myocardial infarction (MI). Three-Bromo-4,5-dihydroxybenzaldehyde (BDB) is a potent antioxidant and natural bromophenol compound derived from red algae. Although BDB has been shown to have an anti-inflammatory
Effect of chronic ethanol administration on bromobenzene liver toxicity in the rat.
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Logi sisse
Female Sprague-Dawley rats were pair-fed a nutritionally adequate liquid diet containing either ethanol or isocaloric carbohydrate for 3 weeks. In vitro studies showed that chronic ethanol pretreatment preferentially increased the liver microsomal biotransformation of bromobenzene to p-bromophenol
Hepatic bromobenzene epoxidation and binding: prevention by ascorbyl palmitate.
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Logi sisse
Bromobenzene undergoes metabolic activation via 2,3- and 3,4-epoxidation catalyzed by the hepatic cytochrome P-450 mixed-function oxidase system. Its reactive metabolites, especially bromobenzene 3,4-oxide, presumably lead to severe centrolobular necrosis. A study of relative rate of binding of
Caspase 3 role and immunohistochemical expression in assessment of apoptosis as a feature of H1N1 vaccine-caused Drug-Induced Liver Injury (DILI).
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Logi sisse
BACKGROUND
Drug-Induced Liver Injury (DILI) changes, occur post exposure to natural or chemical compounds including apoptosis.
OBJECTIVE
To assess the H1N1 vaccine-caused DILI by histochemical and immunohistochemical methods.
METHODS
This 2014's experimental study was conducted on 70 albino rats.
Glutathione conjugates of 2-bromohydroquinone are nephrotoxic.
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Logi sisse
Incubation of either o-bromophenol or 2-bromohydroquinone with rat liver microsomes and 0.25 mM 35S-glutathione (GSH) gave rise to several isomeric 35S-GSH conjugates. A mixture of these isomeric GSH conjugates was prepared chemically and two were purified by HPLC; 1H-NMR spectroscopy revealed that
Nephrotoxicity of phenolic bromobenzene metabolites in the mouse.
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Logi sisse
Bromobenzene, at doses greater than 5.7 mmol/kg, produced renal proximal tubular necrosis and renal functional changes in mice. p-Bromophenol and o-bromophenol were the major urinary phenolic bromobenzene metabolites although m-bromophenol and 4-bromocatechol were also excreted in detectable
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