Leht 1 alates 154 tulemused
The present invention relates to therapeutic associations for the treatment of cancer, comprising an effective amount of a camptothecin, or a camptothecin derivative, with an effective amount of an alkylating agent.
More specifically, the invention relates to anticancer treatments with associations
The present invention relates to therapeutic combinations comprising an effective amount of camptothecin, or a camptothecin derivative such as irinotecan (CPT-11), with an effective amount of an alkylating agent for the treatment of cancer.
More specifically, the invention relates to anticancer
The present invention relates to therapeutic associations for the treatment of cancer, comprising an effective amount of a camptothecin, or a camptothecin derivative, with an effective amount of an alkylating agent.
More specifically, the invention relates to anticancer treatments with associations
This invention relates to methods for treating colon cancer in mammals. More particularly, the invention relates to methods for treating malignant colon tumors and colo-rectal tumors in mammals by administering an effective amount of a tumor-inhibiting camptothecin compound, and consequently
The present invention relates to therapeutic pharmaceutical compositions comprising an effective amount of a pyrimidine derivative in combination with an effective amount of camptothecin or camptothecin derivatives, which are useful for the treatment of cancer.
The invention relates to the treatment
FIELD OF THE INVENTION
The present invention relates to camptothecin compounds, in particular, irinotecan hydrochloride composition formulations, and methods of administering camptothecin compounds such as irinotecan hydrochloride for the treatment of cancer and AIDS, with reduced side
FIELD OF THE INVENTION
The present invention relates to camptothecin compounds, in particular, irinotecan hydrochloride composition formulations, and methods of administering camptothecin compounds such as irinotecan hydrochloride for the treatment of cancer and AIDS, with reduced side
BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to the preparation of the 5(S)-(2'-hydroxyethoxy)-20(S)-camptothecin diastereoisomer of camptothecin and its use for the treatment of cancer.
(2) Description of the Related Art
Camptothecin (CPT) is a pentacyclic
BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to the preparation of the 5(S)-(2'-hydroxyethoxy)-20(S)-camptothecin diastereoisomer of camptothecin and its use for the treatment of cancer.
(2) Description of the Related Art
Camptothecin (CPT) is a pentacyclic
FIELD OF THE INVENTION
The present invention is directed to aromatic esters of camptothecins.
BACKGROUND OF THE INVENTION
Camptothecin, a natural product originally found in China, but now grown in many countries, was isolated and purified by Wall and his coworkers in 1966 (J. Am. Chem. Soc. 88,
FIELD OF THE INVENTION
The present invention is directed to aromatic esters of camptothecins.
BACKGROUND OF THE INVENTION
Camptothecin, a natural product originally found in China, but now grown in many countries, was isolated and purified by Wall and his coworkers in 1966 (J. Am. Chem. Soc. 88,
BACKGROUND OF THE INVENTION
This invention relates to water soluble camptothecin analogs, a pharmaceutical composition comprising a tumor cell growth inhibiting amount of such an analog, and a method of inhibiting the growth of tumor cells sensitive to such an analog in an animal in need
FIELD OF THE INVENTION
The present invention relates to nano- and micro-sized particles of 20-comptothecin and derivatives thereof for pharmaceutical compositions, and use of these particles and compositions containing them for treating cancer, malignant tumors, and the like.
BACKGROUND OF THE
FIELD OF THE INVENTION
The present invention relates to a method for treating pancreatic cancer in humans.
BACKGROUND OF THE INVENTION
20(S)-camptothecin (CPT), a plant alkaloid, was found to have anticancer activity in 1966 (Wall, M., Wani, M. C., Cooke, C. E., Palmer, K. H., McPhail, A. T. and
FIELD OF THE INVENTION
The present invention relates to a method for treating cancer in mammals, more particularly, to a method for treating malignant tumors such as lung, breast, stomach, pancreatic, prostate, bladder, osteosarcoma and ovary carcinomas and malignant melanomas.
BACKGROUND OF THE