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OBJECTIVE
The aim of this study was to investigate whether oral allergy syndrome (OAS) in Japan has a particular association with Japanese cedar (JC) hay fever and which kinds of food allergen cause OAS.
METHODS
The questionnaire was answered by 463 adult asthmatics. Each patient was submitted to
Allergic rhinitis is the most prevalent type I allergy in industrialized countries. Pollen scattering from trees or grasses often induces seasonal allergic rhinitis, which is known as pollinosis or hay fever. The causative pollen differs across different areas and times of the year. Impaired
Cedrela serrata Royle (C. serrata) is a medicinal plant not only used for constructions but also an important conventional medicine for the treatment of various diseases such as; diabetes, jaundice, liver diseases, diarrhea, fever, chronic infantile dysentery, intestinal worms, A presumed rise in the prevalence of atopic diseases in industrialized countries is currently subject to extensive discussion. Due to a lack of epidemiological longitudinal studies, the controversy among the experts was based mainly on speculation. Only recently have data from various European
BACKGROUND
The Japan Environment and Children's Study (JECS) is a nationwide, multicenter, prospective birth cohort investigation launched by the Ministry of Environment in Japan. The purpose of the JECS is to evaluate the influence of prenatal and postnatal exposures to environmental factors on the
Evidence suggests that allergic disease is becoming more common, particularly in industrialized societies. Two studies of schoolchildren from Aberdeen, Scotland aged 8-13 years were undertaken in 1964 and 1989 using identical questionnaires, and found that the reported prevalence of asthma had risen
It may be a coincidence, but it is a fact that the first clear characterization of hay fever began in England where modern industrialization started in Europe. Only at the end of the 20th century were associations of the increasing prevalence of allergy with outdoor air pollution discussed. The
Whole genome scan analyses have revealed that the chromosomal region 3p21.3, which contains a gene cluster of the CC chemokine receptor, is possibly critical for the pathogenesis of allergic inflammation. Japanese cedar pollinosis is mediated by a type I allergy and induces seasonal rhinitis and
BACKGROUND
Japanese cedar pollinosis is the most common form of hay fever in spring in Japan. We have previously demonstrated that single nucleotide polymorphism Pro358Leu of exon 7 in the eosinophil peroxidase (EPO) gene is associated with cedar pollinosis, although the association has not been
Alnus sieboldiana has been planted widely on denuded sites in the Rokko mountains. Its pollination season is in the latter half of that of Japanese cedar. This epidemiologic study was carried out in Ashiya in the 1991 spring hay fever season. The subjects were 532 female residents chosen at random,
Cedrela odorata L. is a native plant of the Amazon region. The bark is used in folk remedies for the treatment of diarrhea, vomiting, fever and inflammation. Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease accompanied by itching. It is a complex disease involving
In Europe and America, the allergen immunotherapy (AIT) for various hay fevers or allergic rhinitis is enforced as causal treatment methods. However, in Japan, the only AIT is subcutaneous immunotherapy (SCIT) for Japanese cedar pollinosis and not so popular due to the long term treatment and the
Immunotherapy for hay fever due to ragweed, grass, birch, and mountain cedar pollens and for asthma due to ragweed, grass, house dust mite, and cat dander allergens relieves symptoms in controlled studies. Clinical improvement is specific for the allergen employed, depends on the dose administered,