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Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer

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This is a pilot study of statin therapy to examine the feasibility of simvastatin use to reduce disease progression in 20 patients with platinum-sensitive ovarian cancer at Cedars-Sinai Medical Center. This study will focus on patients with recurrent platinum sensitive ovarian cancer to increase the

Continuous Alcohol Monitoring for Pancreatitis

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Alcohol is the leading cause of recurrent acute and chronic pancreatitis, which greatly elevates the risk of pancreatic cancer. Reducing alcohol intake in patients with a history of alcoholic pancreatitis prevents progression of pancreatitis. Provider-based education on alcohol reduction has not

Contrast Enhanced Endoscopic Ultrasound in Pancreas Lesions

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The study is a prospective trial of CE- EUS in which the conventional EUS that is part of standard clinical care is conducted after injection of intravenous contrast agent. The study population will include those patients already undergoing endoscopic ultrasound for standard pancreatic indications

Chemoradiation With Enadenotucirev as a Radiosensitiser in Locally Advanced Rectal Cancer

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At present identifying novel radiosensitising agents in colorectal cancer is an area of high need for patients considering sphincter preserving surgery or needing down staging to facilitate surgery. Although the combination of Enadenotucirev with chemoradiation is novel, there is a wealth of

Increasing HPV Vaccination Rates Via Educational Interventions in Schools Located Within Cedars-Sinai Catchment Areas

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Rationale and Significance Infections with human papillomavirus (HPV) can cause cancer of the cervix, vagina, anus, throat, mouth, and penis. Prevention of these HPV-related cancers could be achieved by immunization with the nonavalent (HPV6,11,16,18,31,33,45,52,58) vaccine currently commercially

TRACER [F-18] RDG-K5 Carotid Plaque Imaging Study

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The primary objectives of this exploratory study are: - To assess the uptake of [F-18] RGD-K5 by carotid plaque with PET/MRI imaging in participants prior to carotid endarterectomy and thereby determine if carotid plaque that causes significant stenosis [in participants being considered for carotid

Expression of TET1 Gene in Acute Leukaemia

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"Acute leukemia" is defined by the World Health organization standards, in which greater than 20% of the cells in the bone marrow are blasts (Kabuto et al., 2006). Cure is a realistic goal and is achieved in more than 80% of affected children, although only 20-40% of adults are cured(Rose-Inman and

Personalized Cancer Care at Cedars-Sinai Medical Center Samuel Oschin Comprehensive Cancer Institute

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Targeted therapy in this study can be either off label-use of a U.S. Food and Drug Administration (FDA) approved drug or a clinical trial that includes investigational drugs. Matched targeted therapy outcomes will be compared to the outcomes of patients who were not matched to a treatment. In order

FOCUS:Families OverComing Under Stress

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Despite advances in the development of brief evidence-based programs for families and couples contending with illness, trauma or loss, the support services provided at even top-tier medical facilities are overwhelmingly focused on the individual patient. In most cases, combined treatment with

Emerging From the Haze for Gynecologic Cancer Survivors

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Virtual Reality in Inpatients

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Recent advances in Virtual Reality (VR) technology have made it possible for researchers to develop interventions for a wide variety of disease states, including obesity, pain, impaired motor functioning, and anxiety. Over the last decade, improvements in software and hardware design, as well as

Emerging From the Haze™- Measuring the Impact of a Psycho-education Program on Perceived Cognition After Breast Cancer Treatment

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ColoCare Study - Colorectal Cancer Cohort

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The ColoCare Consortium is a multicenter initiative establishing an international cohort of colorectal cancer (CRC) patients for interdisciplinary studies of CRC prognosis and outcomes with sites at the Fred Hutchinson Cancer Research Center, Seattle (Washington, USA), H. Lee Moffitt Cancer Center

Colour Contrast Sensitivity for the Early Detection of Wet Age-related Macular Degereration (CEDAR)

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Neovascular age‐related macular degeneration (nARMD), which by definition affects the over 50s, accounts for more than 50% of visual impairment certifications in the United Kingdom1 and a recent study2 estimates the prevalence in the UK at 1.2% in individuals aged 50 or more, 2.5% in those over 65,

The Physical and Psychological Benefits of Yoga and Breast Cancer

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Proposed Intervention: 1-hour hatha yoga classes, once a week for a 12-week period. One class will be offered in French, another in English. The class will begin with approximately 10 minutes of pranayama (breathing exercises) and meditation, followed by 30 minutes of yoga poses and ending with 10

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