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The effects of Centella asiatica (L.) Urban on neural differentiation of human mesenchymal stem cells in vitro.

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Centella asiatica (L.) Urban, known as Indian Pennywort, is a tropical medicinal plant from Apiaceae family native to Southeast Asian countries. It has been widely used as a nerve tonic in Ayuverdic medicine since ancient times. However, whether it can substitute for neurotrophic

Protection of mouse brain from paracetamol-induced stress by Centella asiatica methanol extract.

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Centella asiatica (CA) is a medicinal herb traditionally used as a brain tonic in Ayurvedic medicine. Various ethnomedical leads revealed the effective use of CA in the treatment of symptoms associated to oxidative stress and inflammation.The aim of this

Radioprotection of Swiss albino mouse by Centella asiatica extract.

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Centella asiatica, has a considerable reputation in the Indian system of medicine. It is a rasayan (general tonic), brain tonic, improves memory and strengthens the CNS. In view of its multifarious uses, the plant extract was tested for its radioprotective properties. A sublethal dose of Co 60 gamma

In vitro evidence that an aqueous extract of Centella asiatica modulates α-synuclein aggregation dynamics.

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α-Synuclein aggregation is one of the major etiological factors implicated in Parkinson's disease (PD). The prevention of aggregation of α-synuclein is a potential therapeutic intervention for preventing PD. The discovery of natural products as alternative drugs to treat PD and related disorders is

Centella asiatica Improves Physical Performance and Health-Related Quality of Life in Healthy Elderly Volunteer.

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Recently, oxidative stress has been reported to contribute an important role in the decline of physical function as age advances. Numerous antioxidants can improve both physical and psychological performances resulting in the increase of health-related quality of life (HQOL). Therefore, we

Effect of different extracts of Centella asiatica on cognition and markers of oxidative stress in rats.

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Centella asiatica, a plant mentioned in Indian literature has been described to possess CNS effects such as stimulatory-nervine tonic, rejuvenant, sedative, tranquilizer and intelligence promoting property. In the present study aqueous, methanolic and chloroform extracts of C. asiatica were

Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential.

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This paper covers the studies relevant to neuroprotective activity of Centella asiatica (L.) Urban, also known as "Gotu Kola." The plant is native to the Southeast Asia and has been used traditionally as brain tonic in ayurvedic medicine. The neuroprotective effect of C. asiatica has been searched

Matrix metalloproteinase, hyaluronidase and elastase inhibitory potential of standardized extract of Centella asiatica.

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BACKGROUND Centella asiatica (L.) Urban (Apiaceae), a valuable herb described in Ayurveda, is used in the indigenous system of medicine as a tonic to treat skin diseases. OBJECTIVE Centella asiatica methanol extract and its ethyl acetate, n-butanol and aqueous fraction, were subjected for the

Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro.

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Axonal regeneration is important for functional recovery following nerve damage. Centella asiatica Urban herb, also known as Hydrocotyle asiatica L., has been used in Ayurvedic medicine for centuries as a nerve tonic. Here, we show that Centella asiatica ethanolic extract (100 microg mL-1) elicits a

Centella asiatica L. Phytosome Improves Cognitive Performance by Promoting Bdnf Expression in Rat Prefrontal Cortex.

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A wide range of people in the world use natural remedies as primary approaches against illnesses. Accordingly, understanding the mechanisms of action of phytochemicals has become of great interest. In this context, Centella asiatica L. is extensively used, not only as anti-inflammatory or

Inverted U-shaped response of a standardized extract of Centella asiatica (ECa 233) on memory enhancement.

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The herb Centella asiatica has long been considered a memory tonic. A recent review found no strong evidence for improvement of cognitive function, suggesting negative results were due to limitations in dose, standardization and product variation. We used a standardized extract of C. asiatica (ECa

Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A Systematic Review and Meta-analysis.

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Centella asiatica (L.) Urb. has been used as an herbal brain tonic for mental disorders and enhancing memory, but no review of the overall evidence of C. asiatica and cognitive function has been conducted. This study aims to determine the effects of C. asiatica on cognitive function and its related

Ethnobotany of medicinal plants used by the Zeliangrong ethnic group of Manipur, northeast India.

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The Zeliangrong people with their yearlong experiences still depend on the medicinal plants for primary healthcare. Some of the medicinal plants used by the community exhibits established pharmacological activities which signify the importance of the traditional knowledge of the

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Herbal & Natural Medicine

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