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cholesteatoma/phosphatase
Link salvestatakse lõikelauale
Leht 1 alates 32 tulemused
Alkaline and acid phosphatase activity in postauricular skin and cholesteatoma epithelium.
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Alkaline phosphatase activity in cholesteatoma epithelium and skin.
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Expression of annexin II in human middle ear cholesteatoma.
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Annexin II has previously been discovered to have involvements in DNA replication and metabolism, bone resorption, and osteoclast formation. In our work, Western blotting and immunohistostaining studies revealed the presence of annexin II in human cholesteatoma tissue. With monoclonal mouse
Histochemical studies of cholesteatoma.
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Frozen sections of cholesteatomas were compared with postauricular and auditory canal skin and studied using histochemical methods. Several dehydrogenases, lysosomal enzymes and proteolytic activity were studied. Lactate and malate dehydrogenase activity was very strong in the epithelium and
Osteoclasts are not activated in middle ear cholesteatoma.
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It is unclear whether osteoclasts are present and activated in cholesteatomas. We explored the expression of messenger RNA (mRNA) for osteoclast biomarkers and regulating factors in middle ear cholesteatomas to elucidate the level of osteoclast activity in this disease. Bone powder was collected
Clinical and biochemical studies of bone destruction in cholesteatoma.
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The exact causative factor(s) of bone erosion in cholesteatoma are not known. In recent years, the possible role of cytokines has drawn attention. Since the studies on cytokines in cholesteatoma are limited and depend on histopathological methods, the present work approached this subject by
Expression of matrix-degrading cysteine proteinase cathepsin K in cholesteatoma.
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Cholesteatoma is a nonneoplastic lesion of the middle ear space or mastoid that is histologically characterized by a progressive bone erosion of the ossicles and surrounding bone. Several matrix-degrading enzymes have been implicated as mediators of this bone erosion. Because the novel cysteine
Cellular and subcellular events of bone resorption in human and experimental cholesteatoma: the role of osteoclasts.
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An ultrastructural study of the interface between aural cholesteatoma and adjacent bone was performed on specimens obtained from human and experimental gerbilline cholesteatoma. When an enlarging cholesteatoma contacted bone, a large number of monocytes and macrophages accumulated in the area of
A murine model of cholesteatoma-induced bone resorption using autologous dermal implantation.
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OBJECTIVE
To investigate a novel murine model for dermal implant-induced osteolysis analogous to bone resorption observed in middle ear cholesteatoma.
METHODS
Animal experiment.
METHODS
We placed autologous dermal implants on the surface of mouse calvaria. The calvaria were examined at days 1, 3, 5,
Cathepsin activity in cholesteatoma.
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Collagenolytic cathepsin, presumed to play an important role in bone destruction of cholesteatoma, was investigated in cholesteatoma epithelium, subepithelial granulation tissue, skin from the bony external auditory meatus and, temporal bone. The enzyme extracted from tissues was proven to be
Third place--Resident Basic Science Award 1990. Interleukin 1 causing bone destruction in middle ear cholesteatoma.
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We previously reported the localization of interleukin 1 in the epithelial layer of human cholesteatomas. On the basis of other studies that showed interleukin 1 can stimulate fibroblasts and macrophages to produce collagenases and prostaglandins, we then proposed that interleukin 1 may play an
Bone resorption in chronic otitis media. The role of cholesteatoma, a must or an adjunct?
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The paper contains the results of light microscopical, electron microscopical and histochemical examinations of chronic otitis media, with and without cholesteatoma, with special focus on the problems regarding bone resorption. It is demonstrated that bone resorption takes place without the presence
[Angiogenesis in cholesteatoma of the middle ear].
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Middle ear cholesteatoma is characterized by the presence of a keratinizing squamous epithelium with hyperproliferative features. Such growth can only be supported by abundant blood vessels. The presence and distribution of blood vessels in cholesteatoma was studied to determine the mechanisms
Role of interleukin 6 in epithelial hyperproliferation and bone resorption in middle ear cholesteatomas.
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Locally produced pro-inflammatory cytokines are considered to play an important role in the initiation and/or maintenance of inflammatory diseases. In cholesteatomatous lesions there are increased levels of some cytokines and inflammatory mediators like interleukin 1, tumor necrosis factor and
Expression of human intercellular adhesion molecules in middle ear cholesteatoma.
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BACKGROUND
Cell adhesion molecules are cell surface proteins that allow specific cell-cell interactions among leukocytes, as well as between leukocytes and other cells. Because middle ear cholesteatoma is characterized by the presence of leukocyte infiltrates, the presence of the two molecule types
Kõige täiuslikum ravimtaimede andmebaas, mida toetab teadus
- Töötab 55 keeles
- Taimsed ravimid, mida toetab teadus
- Maitsetaimede äratundmine pildi järgi
- Interaktiivne GPS-kaart - märgistage ürdid asukohas (varsti)
- Lugege oma otsinguga seotud teaduspublikatsioone
- Otsige ravimtaimi nende mõju järgi
- Korraldage oma huvisid ja hoidke end kursis uudisteuuringute, kliiniliste uuringute ja patentidega
Sisestage sümptom või haigus ja lugege ravimtaimede kohta, mis võivad aidata, tippige ürdi ja vaadake haigusi ja sümptomeid, mille vastu seda kasutatakse.
* Kogu teave põhineb avaldatud teaduslikel uuringutel
