Five new prenylflavonoids, artocommunols CA (1), CB (2), CC (3), CD (4), and CE (5), were isolated from the cortex of the roots of Artocarpus communis, along with the known compound cyclomorusin. The structures of 1-5 were determined by spectral methods.
The antiinflammatory activities of the isolated flavonoids, including cycloartomunin (1), cyclomorusin (2), dihydrocycloartomunin (3), dihydroisocycloartomunin (4), cudraflavone A (5), cyclocommunin (6), and artomunoxanthone (7), and cycloheterohyllin (8), artonins A (9) and B (10), artocarpanone