The control group included 10 periodontally healthy subjects without signs or symptoms of periodontal disease.

The study group included 15 subjects diagnosed with mild or advanced chronic periodontitis. Each periodontal patient had one non-affected single-rooted tooth (healthy site) and another single-rooted tooth with periodontitis (periodontitis site) with the following features:
Healthy site: a single-rooted tooth with probing depths below or equal to 3 mm without recession and without bleeding on probing.
Periodontitis site: another single-rooted tooth from the same patient with clinical attachment loss equal to or greater than 6 mm and bleeding upon probing.

Periodontal Diseases

Biomarkers

Bone Resorption

In the study group, periodontal scaling and root planning treatment of the 4 quadrants was performed for two consecutive weeks without the use of antiseptics or antibiotics, and the patients were instructed in oral hygiene, including both brushing techniques and proximal hygiene.

periodontal treatment

Impact of Periodontal Treatment on the RANKL/OPG Ratio in Crevicular Fluid

receptor activator of NF-κB ligand.RANKL is a protein that determines the activation of osteoclasts by binding to the RANK membrane receptor that preosteoclates possess.
The ranks wi be measured in μg / μl.

osteoprotegerin.Osteoprogesterian is a soluble protein that acts as a decoy blocked RANK receptor and thus initiating osteoclastogenesis.
The opg will be measured in μg / μl.

Probing depth, is the distance from the free gingival margin to the bottom of the periodontal pocket. This parameter will be measured in mm.

Is the distance from the free cementoenamel junction to the bottom of the periodontal pocket. This parameter will be measured in mm.

Percentage of points with bleeding on probing in relation to the total number of points probed.

dental plaque/protease

Impact of Periodontal Treatment on the RANKL/OPG Ratio in Crevicular Fluid

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