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Following surgical ligation of the middle cerebral artery in the rat, central catecholamine containing neurons were studied using the glyoxylic acid histochemical technique. By 5 days after the ischemic lesion, the density of fluorescent varicosities decreased in both uninjured cerebral cortex and
OBJECTIVE
The aim was to test the hypothesis that chronic sympathetic denervation of the boundaries of a healed myocardial infarction may modify the arrhythmogenic response to programmed electrical stimulation.
METHODS
Electrical induction of ventricular arrhythmias and infarct size were evaluated
The effects of the age of induction and total duration of streptozotocin diabetes on the sympathetic noradrenergic innervation of the rat heart was examined with glyoxylic acid induced histofluorescence to demonstrate the distribution of noradrenergic fibers within the heart, and with high
Stellate ganglia from patients who had succumbed to various diseases were examined by a fluorescent histochemical technique using 2% glyoxylic acid. Catecholamines were detectable in the major neurons, in small intensely fluorescent cells, and in adrenergic fibers with varicosities at levels that
A comparative histochemical and clinical study concerning the state of the intrinsic adrenergic innervation of the human atrial myocardium was carried out, using the glyoxylic acid-induced fluorescence histochemical method. Specimens from the right auricular appendage were obtained during open-heart