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CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims priority to European Patent Application No. 11160557.2 filed on Mar. 31, 2011, the disclosure of which is incorporated herein by reference in its entirety.
BACKGROUND
Cancer is one of the most dreaded diseases of mankind, it is a
TECHNICAL FIELD
The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SK.sub.Ca and IK.sub.Ca channels. In further aspects, the present invention relates to the
FIELD OF INVENTION
This invention relates to cancer therapy. More specifically, this invention comprises novel Shp2 inhibitors, a method to develop new Shp2 inhibitors, and a method of treating cancer using the inhibitors.
BACKGROUND OF THE INVENTION
Tyrosyl phosphorylation regulates human cellular