ketosis/carbohydrate

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Exogenous Ketones in People With Type 1 Diabetes

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The ketone bodies acetoacetate, β‐hydroxybutyrate (βHB) and acetone are small lipid-derived molecules that are produced in the liver under certain conditions such as starvation, very low carbohydrate intake and prolonged glycogen-depleting exercise (Robinson and Williamson, 1980, Balasse and Fery,

Short Term Induction of Ketosis in PKD

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Recently, dietary models inducing ketosis have been shown to inhibit disease progression in animal models of PKD. Those beneficial dietary models included time-restricted feeding (TRF) without caloric reduction, ad libitum administered ketogenic diet (KD) and acute short-term fasting in mouse, rat

Diabetes Journey: An Adolescent Adherence Barriers Intervention

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Type 1 diabetes (T1D) treatment adherence is complex and involves glucose monitoring, counting carbohydrates, and intensive insulin delivery via injections or insulin pump in response to food intake, exercise, and illness to achieve near-normal blood glucose levels. Evidence demonstrates that

Microbiota in Dietary Approach to Obesity

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Keto-diet for Intubated Critical Care COVID-19

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Coronavirus disease (COVID-2019) is a devastating viral illness that originated in Wuhan China in late 2019. The number of confirmed cases worldwide has nearly reached 2 million and more than 125,000 people have died. Early studies from Wuhan reported a mortality rate of 2-3% with lower rates in

Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial Imaging

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Effects of Ketosis on Brain Function in Patients With T1DM

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To test the hypothesis that a ketogenic diet increases hypoglycemia tolerance and improves brain function and cognitive performance during hypoglycemia, the researchers propose a randomized mechanistic study using insulin infusions and neuroimaging. The study will leverage an existing randomized

Very Low Carbohydrate Diets and Glucagon Response in T1DM

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The Effect of Ketogenic Dietary Therapy on Sleep in Adult Epilepsy

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Twenty participants, 10 participants on the modified Atkins diet and 10 control participants, will be enrolled in the study. All participants will fill out validated sleep questionnaires and complete sleep and seizure diaries. Furthermore, all participants will wear actigraphy watches prior to

A Weight Loss RCT Comparing Keyto vs Weight Watchers

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Very Low Carbohydrate Diet as an Adjunctive Therapy for Youth Type 1 Diabetes

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First, to evaluate the feasibility of following each type of VLCD (high protein or high fat), participants will follow a standard carbohydrate diet for 2 weeks, followed by a 1 week transition to a VLCD, and then follow the a high protein VLCD for 2 weeks followed by a high fat VLCD for 2 weeks. The

Preoperative Oral Carbohydrate for Nausea and Vomiting Prevention During Cesarian Section

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Post-operative nausea and vomiting (PONV) in women undergoing subarachnoid anesthesia for Caesarean section is an important clinical problem. Known mechanisms underlying PONV are based on prolonged fasting, hypotension due to concomitant sympatholysis during anesthesia, bradycardia due to increased

Carbohydrate Restriction in Pregnant Women With Gestation Diabetes Mellitus

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Increasing prevalence of obesity and tendency to become pregnant later in life can explain rising prevalence of gestation diabetes (GDM) (1). Diabetes in pregnancy is a major public health issue: it has been shown that the mother's glycemic levels correlates perfectly with child's birth weight,

Dapagliflozin in Physical Exercise in Type 1 Diabetes

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The University of Michigan PCOS Intervention Using Nutritional Ketosis

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Polycystic ovary syndrome (PCOS) is a common and costly ($4.3 billion/year) endocrine disorder that significantly impairs quality of life and increases the risk of obesity and type 2 diabetes as well as hyperandrogenism, infertility, hyperlipidemia, and cardiovascular disease. Diet and lifestyle

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