ovarian cysts/hypoxia

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High Frequency of Ovarian Cyst Development in Vhl2B/+;Snf5+/- Mice.

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The new paradigm of mutations in chromatin-modifying genes as driver events in the development of cancers has proved challenging to resolve the complex influences over disease phenotypes. In particular, impaired activities of members of the SWI/SNF chromatin remodeling complex have appeared in an

Expression of vascular endothelial growth factor (VEGF), hypoxia inducible factor-1alpha (HIF-1alpha), and microvessel density in endometrial tissue in women with adenomyosis.

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Adenomyosis is a disease with a mysterious pathogenesis, defined by an abnormal displacement of the eutopic endometrium deeply and haphazardly inside the myometrium. Angiogenesis has been indicated to play an important role and our aim was to investigate whether vascular endothelial growth factor

Estimation to efficiency of the multifunction method оf endometriosis ovariеs treatment.

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The aim: The aim of the study was to improve the results of treatment of patients with endometriosis by using a combination method of therapy.Materials and methods: For two years, 136 women of reproductive age who underwent laparoscopic surgeries for

Adnexal torsion with dystrophic calcifications in an adolescent: a chronic entity?

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Intermittent pelvic pain caused by ovarian cysts in adolescence may be due to torsion or partial torsion of the ovary. We present a case of 18-year old adolescent with symptomatic left ovarian torsion with calcifications demonstrated by pelvic MRI and ultrasonography prior to surgery. The pathologic

[The congenital central hypoventilation syndrome (CCHS): a late presentation].

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BACKGROUND The congenital central hypoventilation syndrome (CCHS) or Ondine's curse is a rare autosomal dominant disease, characterized by disorders of the autonomic nervous system, with abnormal ventilatory responses to hypercapnia and hypoxia. PHOX2B has been identified as the major gene causing

Iron regulatory protein 2 in ovarian endometrial cysts.

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Ovarian endometrial cysts cause some kinds of ovarian cancer, and iron is considered as one factor of carcinogenesis. In contrast, hypoxia is associated with progression, angiogenesis, metastasis, and resistance to therapy in cancer. We investigated hypoxia-induced perturbation of iron homeostasis

MicroRNA-200 family governs ovarian inclusion cyst formation and mode of ovarian cancer spread.

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Epidemiologic and histopathologic findings and the laying hen model support the long-standing incessant ovulation hypothesis and cortical inclusion cyst involvement in sporadic ovarian cancer development. MicroRNA-200 (miR-200) family is highly expressed in ovarian cancer. Herewith, we show that

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