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Perisinusoidal fibrosis development in experimental hypervitaminosis A and its combination with preliminary Kupffer cells stimulation with prodigiozan was studied in rat liver using light and electron microscopy. Reticular fibers volume density naturally growing after administration of large dozes
The paper presents data of a luminous microscopy of the liver that were obtained by aspiration biopsy in 23 patients with hepato-cerebral dystrophy in comparison with 25 patients with cirrhosis of a hereditary etiology. In the majority of the cases (21 from 23) the method of puncture biopsy of the
The aim of the study was to evaluate the effects of D-penicillamine (cuprenil), encorton and both drugs in combination on fibrotic processes in the rat liver damaged by chronic use of CCl4. The studies comprised 80 white Wistar rats divided into 8 experimental groups. Group I receiving every day
Examinations of stroma of lymph nodes (50 patients) in lympho- and reticulosarcomas revealed three types of alterations of the reticuline carcass: (1) diffuse destructive changes, (2) focal reticuline fibrosis against the background of destructive lesions, and (3) diffuse reticuline fibrosis. The
The results of histological and ultrastructural studies of bone marrow hemopoietic microenvironment carried out in 27 patients with different myelodisplasias are presented. The following morphological peculiarities of bone marrow stromal tissue have been identified: abnormal localisation of immature
Fibrosis of the bone marrow may be present in various hematologic diseases such as myeloproliferative diseases (MPD) and acute myeloid leukemias (AML). In primary myelodysplastic syndromes (MDS) myelofibrosis is a relatively rare event. Patients affected by MDS with myelofibrosis (H-MDS) present