Bariatric Surgery

Bariatric surgery for enrolled patients who fulfill the including criteria

bariatric surgery

Shanghai Tenth People's Hospital, Tongji University School of Medicine

Effects of Bariatric Surgery on Cardiac and Vascular Structure and Function in Obesity

changes of left ventricular mass index representing cardiac structure measured by ultrasound will be seen from baseline at 1 year

changes of value of E and A peak representing cardiac diastolic function measured by ultrasound will be seen from baseline at 1 year

changes of EF representing cardiac systolic function measured by ultrasound will be seen from baseline at 1 year

changes of pulse wave velocity representing vascular structure measured by SphygmoCor will be seen from baseline at 1 year

changes of flow-mediated dilatation representing vascular function measured by UNEX EF will be seen from baseline at 1 year

Ya-Wei Xu

The chief director of department of cardiology

Shanghai 10th People's Hospital

Patients receive cyclosporin (dose-adjusted to pre-established targets) as immunosuppressive calcineurin inhibitor (CNI) and Diabetes Education / Management (therapeutic adjustment to target American Diabetes Association (ADA) criteria)

Patients receive tacrolimus (dose-adjusted to pre-established targets) as CNI and Diabetes Education / Management (therapeutic adjustment to target ADA criteria)

Patients receive cyclosporin (dose-adjusted to pre-established targets) as CNI and Diabetes Education / Management (therapeutic adjustment to target ADA criteria)

Cyclosporin

Tacrolimus

Total

Sex: Female, Male

The count of participants with freedom from insulin therapy post transplant is reported.

Freedom From Insulin Therapy Post Transplant

Values of ≥60 ml/min/1.73 m^2 are considered optimal; ≥30-59 ml/min/1.73 m^2 are indicative of successful graft function; lower values are indicative or graft dysfunction.

Estimated Glomerular Filtration Rate (eGFR) 1 Year Following Transplantation

Count of participants alive at one year post transplantation

Patient Survival at One Year Post Transplantation

Count of Participants With Biopsy Proven Acute Rejection at One Year Post Transplantation

Patients receive cyclosporin (Neoral; dose-adjusted to pre-established targets) as immunosuppressive calcineurin inhibitor (CNI) and Diabetes Education / Management (therapeutic adjustment to target American Diabetes Association (ADA) criteria)

Patients receive tacrolimus (Prograf; dose-adjusted to pre-established targets) as CNI and Diabetes Education / Management (therapeutic adjustment to target ADA criteria)

Overall Study

Stephan Busque, MD

Kidney Transplant

Diabetes Mellitus, Type 2

Diabetic Nephropathy

Dose adjustment to pre-established targets

therapeutic adjustment to target ADA criteria

'Diabetes Education / Management'

Stanford university Hospital and Clinics

Immunosuppression Impact on the Metabolic Control of Kidney Transplant With Pre-Existing Type 2 Diabetes (DM)

Randomized Open Label Study Comparing the Metabolic Control of Kidney Transplant Recipients With Type 2 Diabetes Receiving Either Prograf or Neoral as Part of a ATG Induction, Prednisone Free and Monitored MMF Immunosuppressive Regimen.

stomach diseases/rasvumus

Effects of Bariatric Surgery on Cardiac and Vascular Structure and Function in Obesity

Immunosuppression Impact on the Metabolic Control of Kidney Transplant With Pre-Existing Type 2 Diabetes (DM)

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