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14 tulemused
Anticonvulsant activity of some xanthone derivatives.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
A series of appropriate alkanolamine and amide derivatives of xanthone were prepared and evaluated for anticonvulsant activity using maximal electroshock (MES) and subcutaneous pentylenetetrazole (scMet) induced seizures, and for neurotoxicity (TOX) using the rotorod test on mice and rats. The most
Pharmacological properties of some xanthone derivatives.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
A series of aminoalkanolic derivatives of xanthone were examined in some experimental models of epilepsia, i.e., pilocarpine, aminophylline and pentetrazole-induced seizures. A final objective of this research was to examine the action of these compounds on the central nervous system, namely on
Evaluation of some 2-substituted derivatives of xanthone for anticonvulsant properties.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
A series of alkanolamides and alkanoamines derivatives of xanthone were prepared and evaluated for antiepileptic activity in the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazol seizure threshold (ScMet) assays and for neurotoxicity (TOX). Several analogues from the appropriate
Synthesis and anticonvulsant effects of some aminoalkanolic derivatives of xanthone.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Synthesis and physicochemical properties of alkanolamine derivatives of xanthone are described. Alkanolamines were synthesized by of the reaction of an appropriate aminoalcohol with corresponding 2-bromomethylxanthones. The obtained compounds 1-13 were evaluated for anticonvulsant activity in the
Central activity of new xanthone derivatives with chiral center in some pharmacological tests in mice.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The study was designed to investigate some central effects of chiral xanthone derivatives [(R,S)-2-N-(6-chloro-2-xanthonemethyl)-amino-1-propanol - MH-31, R enantiomer - MH-32 and S enantiomer - MH-33] in mice. The effects of these chiral compounds were examined in picrotoxin-induced seizures,
Aminoalkanolic derivatives of xanthone with potential antiepileptic activity.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Synthesis, physicochemical and anticonvulsant properties of some aminoisopropanoloxy derivatives of 2-xanthone are described. The compounds were prepared by the amination of 2-[(2,3-epoxy)-propoxyl]-xanthone or 2-(3-chloro-2-hydroxy-propoxy)-xanthone. The obtained compounds were evaluated for
Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
A series of new xanthone derivatives with piperazine moiety [1-7] was synthesized and evaluated for their pharmacological properties. They were subject to binding assays for α₁ and β₁ adrenergic as well as 5-HT₁A, 5-HT₆ and 5-HT₇b serotoninergic receptors. Five of the tested compounds were also
Antiarrhythmic and antihypertensive activity of some xanthone derivatives.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Some of appropriate aminoisopropanoloxy derivatives of 4-xanthone were tested for their effect on circulatory system (protection against adrenaline-, barium-, and calcium chloride-induced arrhythmias, as well as hypotensive activity and acute toxicity). The most prominent hypotensive activity was
Pharmacological properties of some aminoalkanolic derivatives of xanthone.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
A series of appropriate aminoisopropanoloxy derivatives of 2-, 3- or 6-xanthone was synthesized and evaluated for anticonvulsant activity in the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole seizure threshold (ScMet) assays and for neurotoxicity (TOX). The most interesting
Neuropharmacological and molecular docking studies of xanthones from Swertia corymbosa.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Anxiety represents a public health problem consistently found to be the most prevalent class of mental disorders among people of all ages. Xanthones possess many biological properties, including neuroprotective, antioxidant or antidepressant-like. In this study, we aimed to investigate
The influence of some aminoalkanolic xanthone derivatives on central nervous and cardiovascular systems in rodents.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
A series of appropriate aminoalkanolic derivatives 2- or 4-methylxanthone was synthesized and evaluated for anticonvulsant activity in the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole seizure threshold (scPtz) assays, and for neurotoxicity (TOX). The most interesting result
γ-Mangostin increases serotonin 2A/2C, muscarinic, histamine and bradykinin receptor mRNA expression.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
OBJECTIVE
γ-Mangostin is a xanthone found in the fruit hulls of Garcinia mangostana L., which have long been used in Southeast Asia as a traditional medicine for the treatment of abdominal pain, dysentery, wound infections, fever and convulsions. Recent studies have revealed that γ-mangostin
Evidence of the mechanism of action of Erythrina velutina Willd (Fabaceae) leaves aqueous extract.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND
Erythrina velutina is traditionally used for sleepiness, convulsions and nervous system excitation in Brazil. Although central effects have been reported for Erythrina velutina, little is known about its mechanism of action.
OBJECTIVE
To investigate the pharmacological evidences of
Anticonvulsant evaluation of aminoalkanol derivatives of 2- and 4-methylxanthone.
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
A series of 17 new aminoalkanol derivatives of 6-methoxy- or 7-chloro-2-methylxanthone as well as 6-methoxy-4-methylxanthone was synthesized and evaluated for anticonvulsant activity. All compounds were verified in mice after intraperitoneal (ip) administration in maximal electroshock (MES) and
Kõige täiuslikum ravimtaimede andmebaas, mida toetab teadus
- Töötab 55 keeles
- Taimsed ravimid, mida toetab teadus
- Maitsetaimede äratundmine pildi järgi
- Interaktiivne GPS-kaart - märgistage ürdid asukohas (varsti)
- Lugege oma otsinguga seotud teaduspublikatsioone
- Otsige ravimtaimi nende mõju järgi
- Korraldage oma huvisid ja hoidke end kursis uudisteuuringute, kliiniliste uuringute ja patentidega
Sisestage sümptom või haigus ja lugege ravimtaimede kohta, mis võivad aidata, tippige ürdi ja vaadake haigusi ja sümptomeid, mille vastu seda kasutatakse.
* Kogu teave põhineb avaldatud teaduslikel uuringutel
