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BACKGROUND
Leukotriene B4 (LTB4), a potent chemokinetic mediator for neutrophils, is enhanced by interleukin-8 (IL-8) and may play a key role in the inflammatory response of asthma.
OBJECTIVE
The aim of the present study was to investigate whether zileuton, a 5-lipoxygenase antagonist known to
BACKGROUND
Recent data indicate that fungi may contribute to increased severity of asthma.
OBJECTIVE
To determine the prevalence of allergy to 15 mold allergens among patients hospitalized because of exacerbation of asthma and to evaluate the relationship between the severity of the disease and
Allergen immunotherapy is the only treatment altering the natural course of IgE-mediated allergies. Whereas the subcutaneous route for immunotherapy (SCIT) has been historically considered as a reference, we discuss herein the relative advantages of the sublingual and oral routes as alternatives to
BACKGROUND
Atopic dermatitis (AD) is an early and important step in the propagation of the allergic march, enhancing food and respiratory allergies via epicutaneous sensitisation to allergens.
OBJECTIVE
To determine the prevalence and patterns of aeroallergen sensitisation, asthma and allergic
We present the case of a 47-year-old man with exercise-induced dyspnea, cough, chest tightness, and recalcitrant chronic rhinosinusitis. Evaluation revealed IgE sensitization to grass, tree, and weed pollen, no evidence of obstruction on spirometry, and a negative methacholine challenge. Diagnostic
BACKGROUND
Patients with allergic rhinitis and bronchial hyperresponsiveness (BHR) may be at higher risk of developing asthma.
OBJECTIVE
To investigate whether reactivity to aeroallergens in skin prick testing (SPT) and serum eosinophil cationic protein levels can be used to predict BHR in allergic
The correlation of pollen allergens, Dermatophagoides pteronyssinus and animal dender was assessed during a two-year period. Results of skin prick test, total and specific IgE UniCAP tests were compared in atopic patients (AP) with the following diagnoses: atopic dermatitis, allergic rhinitis,
In a sample of 583 subjects (303 men and 280 women) intradermal test with 13 inhalatory allergens, total serum IgE (PRIST Phadezym) determination and nonspecific bronchial reactivity measurement by histamin test, were performed. History data on respiratory symptoms was also taken. The following were
In this retrospective study, data on 241 atopic patients treated with specific cutaneous immunotherapy during the 1985-2006 period at Allergy Clinic, University Department of Dermatology and Venereology, were reviewed. The following diagnoses were recorded: atopic dermatitis, pure or in combination