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zirconium/vähk

Link salvestatakse lõikelauale
Leht 1 alates 18 tulemused

Bioimaging Study of 89Zr-M7824 in NSCLC

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Immune checkpoint inhibitors have shown improved treatment outcome in patients with NSCLC; however, there is room to further improve benefits. A novel agent such as M7824, a fusion protein which targets the tumor microenvironment where it blocks both the cell intrinsic PD-L1/PD-1 interaction and the

89Zr-atezolizumab PET Scan and Lobular Breast Cancer

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Logi sisse

Molecular Imaging Using Radiolabeled Atezolizumab to Assess Atezolizumab Biodistribution in Lymphoma Patients

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Patients with a high risk diffuse large B-cell lymphoma (DLBLC) with an international prognostic score (IPI) > 2, have a high risk of relapse even after achieving a metabolic complete remission with cyclophosphamide, doxorubicin, vincristine, prednisone and rituximab (R-CHOP) chemo-immunotherapy.
Participants receive standard of care 18F-FDG-PET/CT and/or 18F-FDG-PET/MRI to assess their cancer for surgical excision. Participants than receive panitumumab-IRDye800 dye and 89Zr-panitumumab, both by intravenous (IV) infusion, on Day 0. Participants will undergo 89Zr-panitumumab PET/CT imaging on

PD-L1 Imaging in Non Small Cell Lung Cancer' (PINNACLE)

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Logi sisse
The programmed death 1 (PD1)/ programmed death ligand 1 (PD-L1) pathway plays an important role in regulating the T-cell anti tumor response. Blocking this interaction with the anti PD-L1 monoclonal antibody avelumab is effective in patients with non-small cell lung cancer (NSCLC) resulting in

A Trial of KB004 in Patients With Glioblastoma

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Logi sisse

89Zr-AMG211 PET Imaging Study

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Logi sisse

MPDL3280A-imaging-IST-UMCG

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The Programmed cell death protein 1 (PD1)/Programmed death-ligand 1 (PD-L1) axis is an important immune checkpoint for T cell activation that is used by tumors to evade the host immune response. Blocking signaling with the PD-L1 antibody MPDL3280A results in ongoing T cell activity and can induce

IMaging PAtients for Cancer Drug selecTion - Metastatic Breast Cancer

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Patient selection for hormone therapy and anti-HER2 therapy is based on the presence of their respective targets, the ER and HER2, as currently assessed on tumor tissue by molecular biological techniques. In primary breast cancer, both ER and HER2 are powerful predictors for response to ER or HER2
Many of these tests and procedures are likely to be part of regular cancer care and may be done even if it turns out that you do not take part in the research study. If you have had some of these tests or procedures recently, they may or may not have to be repeated. - A medical history, which

89Zr-bevacizumab PET Scan in Patients With Relapsing Multiple Myeloma

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Multiple Myeloma (MM) is a clonal B cell disorder characterised by a monoclonal plasma cell population in bone marrow, with bone pain, anaemia, hypercalcaemia, and kidney dysfunction as clinically presenting symptoms. Osseous involvement is one of the most predominant features of patients with MM;

HER2 Imaging Study to Identify HER2 Positive Metastatic Breast Cancer Patient Unlikely to Benefit From T-DM1

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The main objective of the trial is to prospectively evaluate the ability of a zirconium 89 labelled trastuzumab PET, to predict, before initiation of the treatment, treatment failure to a new targeted drug: T-DM1. At the same time, the early FDG-PET/CT, performed after 1 course of T-DM1, will also
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