Effect of Passive Smoking on Oxidative Stress and Dental Caries in Children
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وضعیتتکمیل شده
حامیان مالی
Merve Erkmen Almaz
همکاران
Kırıkkale University
کارازمایی بالینی: NCT04298996
BioSeek: nct04298996
کلید واژه ها
خلاصه
The purpose of the present study was to determine the effect of passive smoking on oxidative stress and dental caries in children.A total of 180 children were included to the study as follows; 90 children exposed to passive smoking, and 90 children in the control group (unexposed controls). Also demographic data were recorded (age, gender, parental education levels, child's tooth-brushing habit and child's daily dietary sugar exposure, family income). Dental examination of children were performed and caries prevalence of the patients were recorded. Unstimulated saliva samples were collected from children. Saliva 'cotinine levels' and oxidative stress markers 'total antioxidant status' (TAS), and' total oxidant status' (TOS) were evaluated by using Enzyme-linked immunosorbent assay (ELISA). The obtained data parameters of the two groups were evaluated and comparison was performed.
تاریخ
| آخرین تأیید شده: | 02/29/2020 |
| اولین ارسال: | 03/03/2020 |
| ثبت نام تخمینی ارسال شد: | 03/03/2020 |
| اولین ارسال: | 03/05/2020 |
| آخرین بروزرسانی ارسال شده: | 03/04/2020 |
| آخرین به روزرسانی ارسال شده: | 03/08/2020 |
| تاریخ شروع مطالعه واقعی: | 11/15/2016 |
| تاریخ تخمین اولیه اولیه: | 04/14/2018 |
| تاریخ برآورد مطالعه: | 08/14/2018 |
شرایط یا بیماری
Oxidative Stress
Dental Caries
Passive Smoking
مداخله / درمان
Diagnostic Test: taking saliva samples to determine oxidative stress markers TAS and TOS
فاز
-
گروههای بازو
| بازو | مداخله / درمان |
|---|---|
| study group (passive smoking children) examining for caries prevalence and taking saliva samples to determine oxidative stress markers TAS and TOS | |
| control group examining for caries prevalence and taking saliva samples to determine oxidative stress markers TAS and TOS |
معیارهای صلاحیت
| سنین واجد شرایط تحصیل | 6 Years به 6 Years |
| جنسیت واجد شرایط مطالعه | All |
| روش نمونه گیری | Non-Probability Sample |
| داوطلبان سالم را می پذیرد | آره |
| شاخص | Inclusion Criteria: -Systemically healthy children Exclusion Criteria: - Uncooperative children - The presence of orthodontic/intraoral appliance - Any disease or condition known to affect oxidative stress |
نتیجه
اقدامات اولیه
1. determining oxidative stress marker in saliva: TAS [1 day (once after the dental examination)]]
Unstimulated saliva samples were collected from children.
2. determining oxidative stress marker in saliva: TOS [1 day (once after the dental examination)]
Unstimulated saliva samples were collected from children.
3. determining caries prevalence [1 day (once for dental examination)]
Children were examined to determine caries prevalence.
