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Pars Plana Ex-Press Shunt in Vitrectomized Eyes

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وضعیتاستخدام
حامیان مالی
Cairo University

کلید واژه ها

خلاصه

Implantation of Ex-Press Minishunt via the pars plana in treatment of secondary glaucoma in vitrectomized eyes achieves promising results avoiding complications of other surgical modalities.

شرح

Ex-Press valve implantation was performed under peribulbar anesthesia (5 mL solution of 2% lidocaine and 2.5 mL of 0.5% bupivicaine [Marcaine]). A fornix-based conjunctival flap was dissected with a conjunctival incision made 2mm from the superior limbus and blunt dissection in the sub-Tenon space. Corneal tractional suture using 7-0 Vicryl was taken for proper exposure then gentle cautery was performed. A 4 × 3 mm × 2/3 the scleral thickness scleral flap was dissected at 11 o'clock centered on a point 3.5mm from limbus.

A cellulose microsponge soaked in 0.4 mg/mL Mitomycin-C solution was applied to the scleral flap, with the conjunctiva draped over the sponge for 3 minutes. The sponge was then removed and the area was washed with irrigating saline solution.

Using a pressure plate for globe fixation and as a measure, three 23G valved vitrectomy cannulae were inserted in the superonasal, superotemporal and inferotemporal quadrants. The superior peripheral retina was examined by indentation to ensure absence of any vitreous and more shaving is done at this area if residual vitreous was seen.

The scleral flap was lifted. With the infusion on, a 25-gauge needle was inserted in the scleral bed 3.5 mm from the limbus, through the pars plana into the vitreous cavity. The direction of insertion should be perpendicular to the scleral bed towards the mid-vitreous cavity. The needle was then removed. There must not be any lateral movement of the needle as this will cause aqueous to flow around the implant. The Ex-Press ® P50 shunt is preloaded on an injector and metal rod is fitted into the lumen of the shunt, attached to the end of the injector. The shunt was then placed through the ostium created with the needle. The angle of entry with the shunt was the same as the angle used to make the ostium. The shunt was rotated 90° so that it enters the eye with the spur facing the long axis of the entry point then it was inserted all the way into the wound followed by rotation to its final position once it is inside the eye so that the external backplate was flush with the scleral bed. The injector has an area on the shaft that was then depressed which retracts the metal rod in the lumen of the shunt. This allows the injector to be free from the lumen of the shunt.

After ensuring proper position of the shunt by examining it from inside the vitreous cavity with indentation, the two superior cannulae were removed and 7-0 Vicryl sutures were taken to ensure the water tightness of the sclerotomies.

The scleral flap was then sutured in place using two 10-0 nylon sutures with a spatulated needle. The tightness of the second suture was adjusted so that there was a good percolation with infusion pressure maintained at 15 mmHg in the vitrectomy machine settings. The last cannula together with the infusion was removed and the sclerotomy was sutured. IOP was adjusted to be between 10 mmHg and 20 mmHg. The conjunctiva was then meticulously closed with running 7-0 Vicryl suture in a watertight fashion. A fluorescein strip was used to make sure the wound was watertight.

During the six postoperative weeks, topical corticosteroids and antibiotics were administered four times a day.

تاریخ

آخرین تأیید شده: 03/31/2019
اولین ارسال: 07/22/2018
ثبت نام تخمینی ارسال شد: 07/22/2018
اولین ارسال: 07/29/2018
آخرین بروزرسانی ارسال شده: 04/17/2019
آخرین به روزرسانی ارسال شده: 04/18/2019
تاریخ شروع مطالعه واقعی: 10/31/2017
تاریخ تخمین اولیه اولیه: 10/31/2019
تاریخ برآورد مطالعه: 10/31/2019

شرایط یا بیماری

Glaucoma Secondary

مداخله / درمان

Device: Express Mini shunt

فاز

فاز 1/فاز 2

معیارهای صلاحیت

سنین واجد شرایط تحصیل 18 Years به 18 Years
جنسیت واجد شرایط مطالعهAll
داوطلبان سالم را می پذیردآره
شاخص

Inclusion Criteria:

- Secondary Glaucoma after vitrectomy not responding to maximum medical treatment

Exclusion Criteria:

- Phakic eyes

- Siliconized eyes

- History of Uveitis

نتیجه

اقدامات اولیه

1. Intraocular pressure control (IOP) [6 month]

IOP less than 18 mmHg

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کاملترین پایگاه داده گیاهان دارویی با پشتیبانی علمی

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  • علایق خود را سازماندهی کنید و با تحقیقات اخبار ، آزمایشات بالینی و حق ثبت اختراع در جریان باشید

علامت یا بیماری را تایپ کنید و در مورد گیاهانی که ممکن است به شما کمک کنند ، بخوانید ، یک گیاه تایپ کنید و بیماری ها و علائمی را که در برابر آن استفاده می شود ، ببینید.
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