[Study on Chemical Constituents of Lonicera similis].

OBJECTIVE

To study the chemical constituents of flower buds of Lonicera similis.

METHODS

The compounds were isolated and repeatedly purified by macroperous resin, silica gel column, gel column, preparation of TLC, and RP C18, chromatography. Their structures were elucidated by physicochemical properties, MS and NMR.

RESULTS

Seven compounds were isolated and identified as 4-hydroxy-γ,3,5-trimethoxybenzenepropanol (1), ursolic acid(2), E-ferulic acid(3), caffeic acid ethyl ester(4), dihydrosyringenin (5), rutin(6) and 6-Daucosterin (7).

CONCLUSIONS

Compounds 1 and 5 are isolated from this genus for the first time, and compounds 2 - 4 are isolated from this plant for the first time.